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Coleridge was a regular user of opium as a relaxant, analgesic, antidepressant, and treatment for numerous health concerns.He wrote Kubla Khan under the drug's influence, but the degree to which he used the drug as a creative enhancement is not precise.
The Romantic era in Britain was, in addition to a time of growth for literature and poetry, a time of increased opium use. Interspersed among importation of opium from the Middle and Far East countries, Britain itself produced a meager amount of opium and utilized it, at least initially, as medicine and also as an ingredient in patent medicines to treat a variety of ailments and diseases.
This is why it is important for schools to implement effective strategies and programs to teach young children about the dangers and consequences of opioid misuse. Although the retention time of adolescents is much lower than adults, educating them from a younger age on opioid misuse should help keep children away from these drugs.
The terms 'opioid' and 'opiate' are sometimes used interchangeably, but the term 'opioid' is used to designate all substances, both natural and synthetic, that bind to opioid receptors in the brain. [4] Opiates are alkaloid compounds naturally found in the opium poppy plant Papaver somniferum. [5] [6]
Other clinically important roles of mu are its involvement in respiratory and cardiovascular functions, gastrointestinal peristalsis, feeding, and mood. [38] These other pathways are important because they explain the side effects of opiate use like respiratory depression at high doses, constipation with chronic use, and addicting properties. [32]
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Opium (or poppy tears, scientific name: Lachryma papaveris) is dried latex obtained from the seed capsules of the opium poppy Papaver somniferum. [4] Approximately 12 percent of opium is made up of the analgesic alkaloid morphine, which is processed chemically to produce heroin and other synthetic opioids for medicinal use and for the illegal drug trade.
Opiate overdose symptoms and signs can be referred to as the "opioid toxidrome triad": decreased level of consciousness, pinpoint pupils and respiratory depression. Other symptoms include seizures and muscle spasms. Sometimes an opiate overdose can lead to such a decreased level of consciousness such that the person will not wake up.