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Folic acid, which is the synthetic form of the vitamin folate, is critical both in pre- and peri-conception. [7] Deficiencies in folic acid may cause neural tube defects (NTDs). Women who had 0.4 mg of folic acid in their systems due to supplementing 3 months before childbirth significantly reduced the risk of NTDs. [29]
Doses of folic acid over 1 mg are prescription only. The amount of non-prescription prenatal vitamins needed to achieve this dose may have too much vitamin A and lead to fetal toxicity. [2] In addition, the U.S Army currently provides female soldiers with optional prenatal supplements to combat high anemia rates in female soldiers. [10]
Dietary supplements such as folic acid and iron are important for a healthy pregnancy. [5] Some dietary supplements can cause side effects and harm to the mother or unborn child. [5] Pregnant women should discuss all dietary supplements with their health care professional to determine the appropriate dosage and which supplements are safe during ...
It is recommended to accompany regular meals with a daily prenatal vitamin supplement that has sufficient folic acid and iron content. [30] If the fetus is predicted to have low birth weight, in addition to the general recommendations, it would be ideal to increase caloric intake, which can be done by having extra Food Guide Servings daily. [30]
The United States Preventive Services Task Force recommends folic acid as the supplement or fortification ingredient, as forms of folate other than folic acid have not been studied. [ 22 ] A meta-analysis of folate supplementation during pregnancy reported a 28% lower relative risk of newborn congenital heart defects . [ 35 ]
The new legislation will require millers to add folic acid to non-wholemeal wheat flour from the end of 2026. Folic acid is a synthetic form of vitamin B9 and is also known as folate.
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