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Generation Scotland is a biobank, a resource of biological samples and information on health and lifestyle from thousands of volunteer donors in Scotland.. The aim of Generation Scotland is to create an ethically sound, family- and population-based infrastructure to identify the genetic basis of common complex diseases. [1]
The Edinburgh Cancer Research Centre was established in The University of Edinburgh (UoE) in close partnership with Cancer Research UK and the NHS Lothian, and has strong links to other Institutes and Colleges conducting cancer research in Edinburgh, in particular the Institute of Genetics & Molecular Medicine. The ECRC follows a partnership ...
The Scottish Intercollegiate Guidelines Network (SIGN) was formed in 1993 and develops and disseminates evidence based clinical practice guidelines. [7] These guidelines contain recommendations for effective practice based on current evidence. SIGN aim to improve the quality of health care for patients in Scotland.
Genetic testing is often done as part of a genetic consultation and as of mid-2008 there were more than 1,200 clinically applicable genetic tests available. [23] Once a person decides to proceed with genetic testing, a medical geneticist, genetic counselor, primary care doctor, or specialist can order the test after obtaining informed consent .
Information from UK registries of death (from 2006) and cancer (Scotland from 1957, England and Wales from 1995) were linked to the main Biobank dataset on an ongoing basis. [39] Data from NHS hospital inpatient records (England from 1996, Scotland from 1997 and Wales from 1998) were linked to the main dataset on an ongoing basis. [39]
One outcome has been the growing availability of elective genetic and genomic testing that are initiated by a patient but still ordered by a physician. [10] Additionally, elective genetic and genomic testing that does not require a physician's order called, direct-to-consumer genetic testing has recently entered the testing landscape. [11]
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Another important issue is the uncertainty of prenatal genetic testing. Uncertainty on genetic testing results from several reasons: the genetic test is associated with a disease but the prognosis and/or probability is unknown, the genetic test provides information different than the familiar disease they tested for, found genetic variants have ...
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