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Micrographia: or Some Physiological Descriptions of Minute Bodies Made by Magnifying Glasses. With Observations and Inquiries Thereupon is a historically significant book by Robert Hooke about his observations through various lenses. It was the first book to include illustrations of insects and plants as seen through microscopes.
A Foldscope is an optical microscope that can be assembled from a punched sheet of cardstock, a spherical glass lens, a light emitting diode (LED) and a diffuser panel, along with a watch battery that powers the LED. [ 4] Once assembled, the Foldscope is about the size of a bookmark. The Foldscope weighs 8 grams [citation needed] and comes in a ...
An operating microscope or surgical microscope is an optical microscope specifically designed to be used in a surgical setting, typically to perform microsurgery. [ 1 ] Design features of an operating microscope are: magnification typically in the range from 4x-40x, components that are easy to sterilize or disinfect in order to ensure cross ...
Negative stain. In microscopy, negative staining is an established method, often used in diagnostic microscopy, for contrasting a thin specimen with an optically opaque fluid. In this technique, the background is stained, leaving the actual specimen untouched, and thus visible. This contrasts with positive staining, in which the actual specimen ...
The notion of acoustic microscopy dates back to 1936 when S. Ya. Sokolov [1] proposed a device for producing magnified views of structure with 3-GHz sound waves. However, due to technological limitations at the time, no such instrument could be constructed, and it was not until 1959 that Dunn and Fry [2] performed the first acoustic microscopy experiments, though not at very high frequencies.
The optical configuration for Fourier ptychography. Fourier ptychography is a computational imaging technique based on optical microscopy that consists in the synthesis of a wider numerical aperture from a set of full-field images acquired at various coherent illumination angles, [1] resulting in increased resolution compared to a conventional microscope.
Super-resolution microscopy is a series of techniques in optical microscopy that allow such images to have resolutions higher than those imposed by the diffraction limit, [1][2] which is due to the diffraction of light. [3] Super-resolution imaging techniques rely on the near-field (photon-tunneling microscopy [4] as well as those that use the ...
In 1964, Adam S. G. Curtis coined the term Interference Reflection Microscopy (IRM), using it in the field of cell biology to study embryonic chick heart fibroblasts. [1][2] He used IRM to look at adhesion sites and distances of fibroblasts, noting that contact with the glass was mostly limited to the cell periphery and the pseudopodia. [1]