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One reason depression is thought to be a pathology is that it causes so much psychic pain and distress. However, physical pain is also very distressful, yet it has an evolved function: to inform the organism that it is being damaged, to motivate it to withdraw from the source of damage, and to learn to avoid such damage-causing circumstances in the future.
The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
Depression is a major cause of morbidity and mortality worldwide, as the epidemiology has shown. [1] Lifetime prevalence estimates vary widely, from 3% in Japan to 17% in India. Epidemiological data shows higher rates of depression in the Middle East, North Africa, South Asia and the United States than in other regions and countries. [2]
Depression is a significant mental illness with physiological and psychological consequences, including sluggishness, diminished interest and pleasure, and disturbances in sleep and appetite. [1] It is predicted that by the year 2030, depression will be the number one cause of disability in the United States and other high-income countries. [2]
Rank theory is an evolutionary theory of depression, developed by Anthony Stevens and John Price, and proposes that depression promotes the survival of genes. [1] Depression is an adaptive response to losing status (rank) and losing confidence in the ability to regain it. The adaptive function of the depression is to change behaviour to promote ...
Depression can have multiple, sometimes overlapping, origins. Depression can be a symptom of some mood disorders, some of which are also commonly called depression, such as major depressive disorder, bipolar disorder and dysthymia. [7] Additionally, depression can be a normal temporary reaction to life events, such as the loss of a loved one.
Image credits: historycoolkids #3. This is the grave of Leonard Matlovich. After serving three tours in Vietnam, Matlovich became a recipient of the Bronze Star and Purple Heart.
Melancholia was a far broader concept than today's depression; prominence was given to a clustering of the symptoms of sadness, dejection, and despondency, and often fear, anger, delusions and obsessions were included. [3] Physicians in the Persian and then the Muslim world developed ideas about melancholia during the Islamic Golden Age.
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