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The primary effector then has an action, which creates a signal that can diffuse within the cell. This signal is called the "second (or secondary) messenger." The secondary messenger may then activate a "secondary effector" whose effects depend on the particular secondary messenger system. [citation needed]
Category for the second messenger system. Pages in category "Second messenger system" This category contains only the following page.
Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons. Neuromodulators typically bind to metabotropic, G-protein coupled receptors (GPCRs) to initiate a second messenger signaling cascade that induces a broad, long-lasting signal.
cAMP was discovered by Earl Sutherland and Ted Rall in the mid 1950s. cAMP is considered a secondary messenger along with Ca 2+.Sutherland won the Nobel Prize in 1971 for his discovery of the mechanism of action of epinephrine in glycogenolysis, that requires cAMP as secondary messenger.
In a project separate and apart from the Palm Beach Gardens' work, the county and West Palm Beach have joined forces to seek a state grant to upgrade 13 traffic signals along a 1.9-mile route east ...
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Akt resides in the cytosol in an inactive conformation, until the cell is stimulated and it translocates to the plasma membrane. The Akt PH domain has a high affinity for second messenger PI(3,4,5)P 3, binding to it preferentially over other phosphoinositides. [11] Thus PI3K activity is essential for translocation of Akt to the membrane.
MOSCOW (Reuters) -Russia's state communications watchdog Roskomnadzor said that Signal, an encrypted messaging app, had been blocked in the country for violating laws linked to anti-terrorist ...