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  2. Linaclotide - Wikipedia

    en.wikipedia.org/wiki/Linaclotide

    Linaclotide, like the endogenous guanylin and uroguanylin it mimics, is an agonist that activates the cell surface receptor of guanylate cyclase 2C (GC-C). [12] [4] [14] The medication binds to the surface of the intestinal epithelial cells. [4] Linaclotide is minimally absorbed and it is undetectable in the systemic circulation at therapeutic ...

  3. Lubiprostone - Wikipedia

    en.wikipedia.org/wiki/Lubiprostone

    A 2018 pooled analysis from three phase III, randomized, double-blind, placebo-controlled studies on usage for Opioid-Induced Constipation, found that the numbers of patients reporting adverse effects were similar in both the lubiprostone and placebo treatment groups for all opioid classes (P ≥ 0.125); however, gastrointestinal adverse ...

  4. The eating pattern focuses on whole foods and plant foods that are nutrient-dense. According to experts and the Mayo Clinic, these may include: Whole grains. Fruits. Vegetables. Oily fish. Nuts. Seeds

  5. Dopamine antagonist - Wikipedia

    en.wikipedia.org/wiki/Dopamine_antagonist

    Dopamine receptor flow chart. Dopamine receptors are all G protein–coupled receptors, and are divided into two classes based on which G-protein they are coupled to. [1] The D 1-like class of dopamine receptors is coupled to Gα s/olf and stimulates adenylate cyclase production, whereas the D 2-like class is coupled to Gα i/o and thus inhibits adenylate cyclase production.

  6. HPV 'cures' are popping up online, but here's the truth about ...

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    Ongoing lawsuits allege Merck didn’t fully disclose severe and long-term side effects. A condition plaintiffs allege they received from the vaccine is postural orthostatic tachycardia syndrome ...

  7. Midodrine - Wikipedia

    en.wikipedia.org/wiki/Midodrine

    Side effects of midodrine include hypertension (high blood pressure), paresthesia, itching, goosebumps, chills, urinary urgency, urinary retention, and urinary frequency. [3] Midodrine is a prodrug of its active metabolite desglymidodrine. [3] [1] This metabolite acts as a selective agonist of the α 1-adrenergic receptor.

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  9. Doctor Warns of the Dangerous Mistake You're Making During a ...

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    “These medications are available over the counter, but they are the sprays that noses can get ‘hooked’ on and have side effects, so always follow the instructions on the package closely.”

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