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English: The poliovirus affects the motor neurons of the anterior horn cells, or the ventral (front) grey matter section in the spinal column, which control movement of the trunk and limb muscles including the intercostal muscles.
Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
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Poliovirus is, however, strictly a human pathogen, and does not naturally infect any other species (although chimpanzees and Old World monkeys can be experimentally infected). [40] The CD155 gene appears to have been subject to positive selection. [41] The protein has several domains of which domain D1 contains the polio virus binding site.
In extreme cases polio can cause paralysis, usually in the legs, although movement typically comes back within a few weeks or months. However, it can be life-threatening if it paralyses the ...
Post-polio syndrome (PPS, poliomyelitis sequelae) is a group of latent symptoms of poliomyelitis (polio), occurring in more than 80% of polio infections. The symptoms are caused by the damaging effects of the viral infection on the nervous system and typically occur 15 to 30 years after an initial acute paralytic attack.
The virus infects the throat and intestines, and can cause flu-like symptoms. Paralysis from the polio virus is rare. This year, polio cases have been detected in New York state, London and Jerusalem.
The white space represents a disruption of the nerve fibers, resulting in a loss of nerve supply to the muscle fibers. Denervation is any loss of nerve supply regardless of the cause. If the nerves lost to denervation are part of neural communication to an organ system or for a specific tissue function, alterations to or compromise of ...