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This disease also impacts other animals such as monkeys, mice, and dogs. While certain gene deletions are more frequent than others, novel mutations resulting in Krabbe disease have been discovered worldwide. Most commonly, the underlying cause of the disease is a deletion of a GALC gene, which causes a deficiency in the GALC enzyme.
Infectious canine hepatitis (ICH) is an acute liver infection in dogs caused by Canine mastadenovirus A, formerly called Canine adenovirus 1 (CAV-1). Canine mastadenovirus A also causes disease in wolves , coyotes , and bears , and encephalitis in foxes . [ 1 ]
Macrovesicular steatosis is the most common form and is typically associated with alcohol, diabetes, obesity, and corticosteroids. Acute fatty liver of pregnancy and Reye's syndrome are examples of severe liver disease caused by microvesicular fatty change. [19] The diagnosis of steatosis is made when fat in the liver exceeds 5–10% by weight.
The most common form in dogs is multicentric, involving the lymph nodes. [165] Fibrosarcoma is a malignant tumor that most commonly occurs in the mouth in dogs, and less commonly in the skin, subcutis, and bones. [6] Aggressive fibromatosis, also known as desmoid fibromatosis, a type of non-metastasizing soft-tissue sarcoma, may occur in dogs ...
A lipid storage disorder (or lipidosis) is any one of a group of inherited metabolic disorders in which harmful amounts of fats or lipids accumulate in some body cells and tissues. [1] People with these disorders either do not produce enough of one of the enzymes needed to metabolize and break down lipids or, they produce enzymes that do not ...
Joyce Crommett breeds a type of dog that, typically, lives fewer than ten years: Cavalier King Charles Spaniels. One of them, Billy, has become one of the first dozen pets to be injected with a ...
Hepatic microvascular dysplasia (HMD or MVD) or portal atresia is a disorder where mixing of venous blood and arterial blood in the liver occurs at the microscopic level. It occurs most commonly in certain dog breeds such as the Cairn and Yorkshire terriers although any dog breed may be at risk. [1] [2] [3] This disease may also be found in cats.
Multicentric lymphoma has a better response to treatment than the gastrointestinal form, but infection with FeLV worsens the prognosis. [1] About 75% of cats treated with chemotherapy for lymphoma go into remission. Unfortunately, after an initial remission, most cats experience a relapse, after which they have a median survival of 6 months.