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The majority of the current data supports the concept that bone mass is controlled by LRP5 through the osteocytes. [26] Mice with the same Lrp5 gain-of-function mutations as also have high bone mass. [27] The high bone mass is maintained when the mutation only occurs in limbs or in cells of the osteoblastic lineage. [17] Bone ...
Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).
before migration, FileVault must be disabled at the source. If transferring FileVault data from a previous Mac that uses 10.4 using the built-in utility to move data to a new machine, the data continues to be stored in the old sparse image format, and the user must turn FileVault off and then on again to re-encrypt in the new sparse bundle format.
Activation of trigger points may be caused by a number of factors, including acute or chronic muscle overload, activation by other trigger points (key/satellite, primary/secondary), disease, psychological distress (via systemic inflammation), homeostatic imbalances, direct trauma to the region, collision trauma (such as a car crash which stresses many muscles and causes instant trigger points ...
Receptors for myokines are found on muscle, fat, liver, pancreas, bone, heart, immune, and brain cells. [2] The location of these receptors reflects the fact that myokines have multiple functions. Foremost, they are involved in exercise-associated metabolic changes, as well as in the metabolic changes following training adaptation. [ 1 ]
An association between osteoporosis, another disease characterized by the degradation of bony tissue, and sarcopenia, the age-related degeneration of muscle mass and quality have also been found. [56] Whether this link is a result of direct regulation or a secondary effect through muscle mass is not known.
MyoD, also known as myoblast determination protein 1, [5] is a protein in animals that plays a major role in regulating muscle differentiation.MyoD, which was discovered in the laboratory of Harold M. Weintraub, [6] belongs to a family of proteins known as myogenic regulatory factors (MRFs). [7]
An aponeurosis (/ ˌ æ p ə nj ʊəˈr oʊ s ɪ s /; pl.: aponeuroses) is a flattened tendon [1] by which muscle attaches to bone or fascia. [2] Aponeuroses exhibit an ordered arrangement of collagen fibres, thus attaining high tensile strength in a particular direction while being vulnerable to tensional or shear forces in other directions. [1]