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Alkaline tide (mal del puerco) refers to a condition, normally encountered after eating a meal, where during the production of hydrochloric acid by the parietal cells in the stomach, the parietal cells secrete bicarbonate ions across their basolateral membranes and into the blood, causing a temporary increase in blood pH. [1]
Conventionally, a leukocytosis exceeding 50,000 WBC/mm 3 with a significant increase in early neutrophil precursors is referred to as a leukemoid reaction. [2] The peripheral blood smear may show myelocytes, metamyelocytes, promyelocytes, and rarely myeloblasts; however, there is a mixture of early mature neutrophil precursors, in contrast to the immature forms typically seen in acute leukemia.
Meaning Origin language and etymology Example(s) halluc-to wander in mind Latin ālūcinor, to wander in mind hallucinosis, hallucination hem(at)-, haem(ato)-of or pertaining to blood: Latin hæma [citation needed], from Greek αἷμα, αἱματ-(grc), blood hematology, older form haematology: hema-, hemo-blood Greek αἷμα, (grc), blood
Combined with the resulting alkaline tide, this leads to hypochloremic metabolic alkalosis (low chloride levels together with high HCO − 3 and CO 2 and increased blood pH) and often hypokalemia (potassium depletion). The hypokalemia is an indirect result of the kidney compensating for the loss of acid.
The term acidemia describes the state of low blood pH, when arterial pH falls below 7.35 (except in the fetus – see below) while acidosis is used to describe the processes leading to these states. The use of acidosis for a low pH creates an ambiguity in its meaning.
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Acid–base homeostasis is the homeostatic regulation of the pH of the body's extracellular fluid (ECF). [1] The proper balance between the acids and bases (i.e. the pH) in the ECF is crucial for the normal physiology of the body—and for cellular metabolism. [1]
Ion trapping is the reason why basic (alkaline) drugs are secreted into the stomach (for example morphine), where pH is acidic, and acidic drugs are excreted in urine where the conditions are alkaline.
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