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Therefore, removal of the spleen runs the risk of overwhelming post-splenectomy infection, a medical emergency and rapidly fatal disease caused by the inability of the body's immune system to properly fight infection following splenectomy or asplenia. [1] Common indications for splenectomy include trauma, tumors, splenomegaly or for ...
An overwhelming post-splenectomy infection (OPSI) is a rare but rapidly fatal infection occurring in individuals following removal (or permanent dysfunction) of the spleen. The infections are typically characterized by either meningitis or sepsis , and are caused by encapsulated organisms including Streptococcus pneumoniae . [ 3 ]
Splenic artery embolization is a minimally invasive procedure and, where successful, avoids splenectomy. If an individual's spleen is enlarged, as is frequent in mononucleosis , most physicians will advise against activities (such as contact sports ) where injury to the abdomen could be catastrophic.
Splenic infarct seen on CT Healed splenic infarct. Several factors may increase the tendency for clot formation, such as specific infections (such as infectious mononucleosis, [9] [dubious – discuss] [better source needed] cytomegalovirus infection, [10] malaria, [11] or babesiosis [12]), inherited clotting disorders (thrombophilia, such as Factor V Leiden, antiphospholipid syndrome ...
Acquired asplenia occurs for several reasons: . Following splenectomy due to splenic rupture from trauma or because of tumor; After splenectomy with the goal of interfering with splenic function, as a treatment for diseases (e.g. idiopathic thrombocytopenic purpura, thalassemia, spherocytosis), in which the spleen's usual activity exacerbates the disease
A necessary requirement for splenosis is the rupture of the spleen, through a traumatic injury (such as a car wreck) or abdominal surgery, especially splenectomy.Splenosis in the abdominal category may occur in up to 65% of traumatic ruptures of the spleen. [3]
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Splenosis is a condition where displaced pieces of splenic tissue (often following trauma or splenectomy) autotransplant in the abdominal cavity as accessory spleens. [ 28 ] Polysplenia is a congenital disease manifested by multiple small accessory spleens, [ 29 ] rather than a single, full-sized, normal spleen.