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Duration of treatment with atorvastatin is unlikely to increase the risk of muscle-related side effects as most occur within the first year of treatment, after which the risk is not increased further. [64] The known cardiovascular benefits of atorvastatin over time outweigh the low risk of muscle-related side effects. [65] [64]
The Federal Trade Commission (FTC), along with the New York State Attorney General's office, is angling to give a Wisconsin-based supplement company a legal battle it won't soon forget.Their case ...
Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug. In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [ 1 ]
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
Tuesday morning, they took up more reviews of the evidence. By now, according to the jury forewoman, it seemed clear that most jurors thought the plaintiff should win. They voted in the middle of the day, she says, and it was 11-1 that Johnson & Johnson had failed to warn the Pledgers, and the same 11-1 that the failure to warn had caused ...
The most important adverse side effects are muscle problems, an increased risk of diabetes mellitus, and increased liver enzymes in the blood due to liver damage. [ 5 ] [ 66 ] Over 5 years of treatment statins result in 75 cases of diabetes, 7.5 cases of bleeding stroke , and 5 cases of muscle damage per 10,000 people treated. [ 35 ]
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Soon after the meeting to deal with, and put aside, the concerns about the drug’s safety when taken by seniors, it became clearer that serious side effects in children might be an equally significant problem. The Janssen doctors and statisticians now had more complete results from the long-term study of children and adolescents using Risperdal.