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This class of zinc fingers can have a variety of functions such as binding RNA and mediating protein-protein interactions, but is best known for its role in sequence-specific DNA-binding proteins such as Zif268 (Egr1). In such proteins, individual zinc finger domains typically occur as tandem repeats with two, three, or more fingers comprising ...
n/a Ensembl ENSG00000181896 n/a UniProt Q8IZC7 n/a RefSeq (mRNA) NM_001300949 NM_033204 n/a RefSeq (protein) NP_001287878 NP_149981 n/a Location (UCSC) Chr 19: 19.67 – 19.68 Mb n/a PubMed search n/a Wikidata View/Edit Human Zinc finger protein 101 is a protein that in humans is encoded by the ZNF101 gene. Function Zinc finger proteins (ZNFs), such as ZNF101, bind nucleic acids and perform ...
This gene on the X chromosome is structurally similar to a related gene on the Y chromosome ().It encodes a member of the krüppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers.
In molecular biology the ZZ-type zinc finger domain is a type of protein domain that was named because of its ability to bind two zinc ions. [1] These domains contain 4-6 Cys residues that participate in zinc binding (plus additional Ser/His residues), including a Cys-X2-Cys motif found in other zinc finger domains.
In molecular biology, GATA zinc fingers are zinc-containing domains found in a number of transcription factors (including erythroid-specific transcription factor and nitrogen regulatory proteins). Some members of this class of zinc fingers specifically bind the DNA sequence (A/T)GATA(A/G) in the regulatory regions of genes., [1] giving rise to ...
Zinc finger E-box-binding homeobox 2 is a protein that in humans is encoded by the ZEB2 gene. [5] The ZEB2 protein is a transcription factor that plays a role in the transforming growth factor β (TGFβ) signaling pathways that are essential during early fetal development.
Zinc finger protein 91 homolog is a protein that in humans is encoded by the ZFP91 gene. [5] [6] The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins.
70227 Ensembl ENSG00000160321 ENSMUSG00000068959 UniProt O43345 n/a RefSeq (mRNA) NM_001329971 NM_001329972 NM_001329973 NM_001329974 NM_007153 NM_001004139 RefSeq (protein) NP_001316900 NP_001316901 NP_001316902 NP_001316903 NP_009084 n/a Location (UCSC) Chr 19: 21.93 – 22.01 Mb Chr 7: 39.17 – 39.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Zinc finger protein 208 is a ...