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Codeine/paracetamol, also called codeine/acetaminophen and co-codamol, is a compound analgesic, comprising codeine phosphate and paracetamol (acetaminophen). Codeine/paracetamol is used for the relief of mild to moderate pain when paracetamol or non-steroidal anti-inflammatory drugs (NSAIDs; such as ibuprofen, aspirin, and naproxen) alone do not sufficiently relieve symptoms.
10 mg dihydrocodeine as co-dydramol 10/500, this is also the preparation to be dispensed if no strength is specified on a prescription. 20 mg dihydrocodeine as co-dydramol 20/500 (e.g. branded products Paracod 500/20 and Remedeine). 30 mg dihydrocodeine as co-dydramol 30/500 (e.g. branded products Paracod 500/30 and Remedeine Forte).
Codeine is used to treat mild to moderate pain. [4] It is commonly used to treat post-surgical dental pain. [13]Weak evidence indicates that it is useful in cancer pain, but it may have increased adverse effects, especially constipation, compared to other opioids. [14]
Approved indication for dihydrocodeine is the management of moderate to moderately severe pain as well as coughing and shortness of breath. As is the case with other drugs in this group, the antitussive dose tends to be less than the analgesic dose, and dihydrocodeine is a powerful cough suppressant like all other members of the immediate codeine family (see below) and their cousins ...
AC&C is available in different formulations containing varying amounts of codeine. Formulations containing 8 mg or less of codeine ("AC&C 8" or "222") are typically available from pharmacies over the counter. A prescription is not required, but the medication must be requested from the pharmacist.
Therefore, one could extract all 256mg of Codeine Phosphate in a standard 8/500mg Co-codamol pack of 32 in a comparatively tiny amount of liquid. Even if the user starts the CWE process with 50ml water, (which, theoretically could hold 200g codeine phosphate), the maximum amount of paracetamol consumed will be 450mg (50ml*9mg/ml=450mg), which ...
So when I go to the page for Tylenol, it states that Tylenol 1 contains 8 mg codeine, 2 contains 15 mg, 3 contains 30 mg, 4 contains 60 mg (all of which, so far, I know first-hand to be correct) and finally, that Tylenol 5 contains 90 mg of codeine. However, this page states that they only go up to Tylenol 4 and that 60 mg is the maximum dosage ...
Paracetamol's bioavailability is dose-dependent: it increases from 63 % for 500 mg dose to 89 % for 1000 mg dose. [6] Its plasma terminal elimination half-life is 1.9–2.5 hours, [ 6 ] and volume of distribution is roughly 50 L. [ 132 ] Protein binding is negligible, except under the conditions of overdose, when it may reach 15–21 %. [ 6 ]