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Some authors use the term Cox proportional hazards model even when specifying the underlying hazard function, [14] to acknowledge the debt of the entire field to David Cox. The term Cox regression model (omitting proportional hazards) is sometimes used to describe the extension of the Cox model to include time-dependent factors. However, this ...
The Cox PH regression model is a linear model. It is similar to linear regression and logistic regression. Specifically, these methods assume that a single line, curve, plane, or surface is sufficient to separate groups (alive, dead) or to estimate a quantitative response (survival time).
In full generality, the accelerated failure time model can be specified as [2] (|) = ()where denotes the joint effect of covariates, typically = ([+ +]). (Specifying the regression coefficients with a negative sign implies that high values of the covariates increase the survival time, but this is merely a sign convention; without a negative sign, they increase the hazard.)
As compared to regression analysis, which creates a formula that health care providers can use to calculate the probability that a patient has a disease, recursive partition creates a rule such as 'If a patient has finding x, y, or z they probably have disease q'. A variation is 'Cox linear recursive partitioning'. [2]
A time-varying covariate (also called time-dependent covariate) is a term used in statistics, particularly in survival analysis. [1] It reflects the phenomenon that a covariate is not necessarily constant through the whole study Time-varying covariates are included to represent time-dependent within-individual variation to predict individual responses. [2]
A "one in 20 rule" has been suggested, indicating the need for shrinkage of regression coefficients, and a "one in 50 rule" for stepwise selection with the default p-value of 5%. [ 4 ] [ 6 ] Other studies, however, show that the one in ten rule may be too conservative as a general recommendation and that five to nine events per predictor can be ...
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Extensions of the Cox proportional hazard models are popular models in social sciences and medical science to assess associations between variables and risk of recurrence, or to predict recurrent event outcomes. Many extensions of survival models based on the Cox proportional hazards approach have been proposed to handle recurrent event data.