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2. Here's how Tylenol holds up against other common pain relievers

   www.aol.com/heres-tylenol-holds-against-other...

   The recommended dose of Tylenol for adults is 325 to 650 milligrams every four to six hours. You should not have more than 3,000 to 4,000 milligrams of Tylenol in a span of 24 hours, recommends Walia.

3. Paracetamol - Wikipedia

   en.wikipedia.org/wiki/Paracetamol

   The recommended maximum daily dose for an adult is three to four grams. [27] [39] Higher doses may lead to toxicity, including liver failure. [40] Paracetamol poisoning is the foremost cause of acute liver failure in the Western world, and accounts for most drug overdoses in the United States, the United Kingdom, Australia, and New Zealand. [41 ...

4. Paracetamol poisoning - Wikipedia

   en.wikipedia.org/wiki/Paracetamol_poisoning

   The toxic dose of paracetamol is highly variable. In general the recommended maximum daily dose for healthy adults is 4 grams. [17] [18] Higher doses lead to increasing risk of toxicity. In adults, single doses above 10 grams or 200 mg/kg of bodyweight, whichever is lower, have a reasonable likelihood of causing toxicity.

5. Therapeutic index - Wikipedia

   en.wikipedia.org/wiki/Therapeutic_index

   The maximum dose is used, rather than a lower dose, to reduce the number of test subjects (and, among other things, the cost of testing), to detect an effect that might occur only rarely. This type of analysis is also used in establishing chemical residue tolerances in foods. Maximum tolerated dose studies are also done in clinical trials.

6. FDA Takes Steps to Limit Acetaminophen in Drugs

   www.aol.com/2011/01/13/fda-takes-steps-to-limit...

   The Food and Drug Administration has announced it is taking steps to limit the amount of acetaminophen in prescription drugs, and to require boxed warnings on all prescription products that ...

7. Pain ladder - Wikipedia

   en.wikipedia.org/wiki/Pain_ladder

   The WHO guidelines recommend prompt oral administration of drugs ("by the mouth") when pain occurs, starting, if the patient is not in severe pain, with non-opioid drugs such as paracetamol (acetaminophen) or aspirin, [1] with or without "adjuvants" such as non-steroidal anti-inflammatory drugs (NSAIDs) including COX-2 inhibitors.