Search results
Results from the WOW.Com Content Network
The dorsal root ganglion, more recently referred to as the spinal ganglion, is a collection of neuronal cell bodies of sensory neurons. It is the most common type of sensory ganglion in the human body. Each cell body in the ganglion belongs to what is considered to be a pseudounipolar neuron.
Dorsal nerve roots carry sensory neural signals to the central nervous system (CNS) from the peripheral nervous system (PNS). Anatomically, a dorsal root ganglion (DRG) emerges from the dorsal root of the spinal nerves (see Image. Dorsal Root Ganglion and Proximal Nerve Roots in the Spinal Foramen).
A dorsal root ganglion (or spinal ganglion; also known as a posterior root ganglion [1]) is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve. The cell bodies of sensory neurons known as first-order neurons are located in the dorsal root ganglia.
The dorsal root ganglia are collections of the cell bodies of sensory neurons located lateral to the spinal cord emerging at each spinal level. They are responsible for conveying various sensory stimuli, including pain, touch, vibration, proprioception, and temperature, from the peripheral nervous system to the central nervous system.
The cell bodies of the posterior root neurons are not located in the central grey matter in the spinal cord, but instead in a structure called the spinal/dorsal root ganglion. The anterior and posterior roots join to form the spinal nerve proper, containing a mixture of sensory, motor, and autonomic fibers.
The dorsal nerve roots enter the spinal cord along the postero-lateral sulcus and ventral roots along the anterolateral sulcus. The dorsal root shows a swelling called dorsal nerve root ganglion (spinal ganglion). This ganglion contains cell bodies of pseudounipolar sensory neurons.
The dorsal root ganglion (DRG) houses the cell bodies of primary sensory neurons and projects axons to both the peripheral site of injury and the dorsal horn of the spinal cord. Hence, it is conceivable that the DRG is a major site of nociceptive processing in both adaptive and maladaptive pain states.
The dorsal roots leave the dorsal horn and dorsolateral white matter, coalesce into two bundles and enter the dorsal root ganglion (DRG) in the intervertebral foramen. Immediately distal to the ganglion, the dorsal and ventral roots unite and form a trunk, the spinal nerve.
Dorsal root ganglion (DRG) is the cell body of peripheral axon before it enters the spinal cord and contains both chemokine and opioid receptors. All opioid receptors have been identified in DRG with a higher proportion of MOP (50%) overlapping with rest of opioid receptors ( Moy et al., 2020 ).
The dorsal root ganglia are nodules that lie along the spinal column and they play a key role in pain perception. Under normal circumstances, dorsal root ganglia have scant sympathetic innervation. Nevertheless, trauma and/or infection trigger sympathetic sprouting within DRG via nerve growth factor overexpression.