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Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...
Theriocide – the act of killing an animal by a human (Ancient Greek: therion "wild animal, beast"). Vermicide – an agent used to kill parasitic intestinal worms. Virucide (also viricide) – an agent capable of destroying or inhibiting viruses. Vulpicide (also vulpecide) – the killing of a fox by methods other than by hunting it with hounds.
Captive bolt pistol. A captive bolt pistol (also known as a captive bolt gun, a cattle gun, a stunbolt gun, a bolt gun, a stun gun and a stunner) is a device used for the stunning of animals prior to slaughter. The goal of captive bolt stunning is to inflict a forceful strike on the forehead with the bolt in order to induce unconsciousness.
However, orexin-B shows a 5- to 10-fold selectivity for orexin receptor type 2, whilst orexin-A is equipotent at both receptors. [2] [3] Several orexin receptor antagonists are in development for potential use in sleep disorders. [4] The first of these, suvorexant, has been on the market in the United States since 2015. [5]
structure summary. Orexin receptor type 2 (Ox2R or OX2), also known as hypocretin receptor type 2 (HcrtR2), is a protein that in humans is encoded by the HCRTR2 gene. [5] It should not be confused for the protein CD200R1 which shares the alias OX2R but is a distinct, unrelated gene located on the human chromosome 3.
Euthanasia. Animal euthanasia (euthanasia from Greek: εὐθανασία; "good death") is the act of killing an animal humanely, most commonly with injectable drugs. Reasons for euthanasia include incurable (and especially painful) conditions or diseases, [1] lack of resources to continue supporting the animal, or laboratory test procedures.
Last year, Bill Gates reported that globally, mosquitos are the deadliest animals for humans at 725,000 deaths—mostly through the transmission of malaria and other diseases. He also tweeted they ...
Xylazine is a common veterinary drug used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle, and other mammals. [2] In veterinary anesthesia, it is often used in combination with ketamine. Veterinarians also use xylazine as an emetic, especially in cats. [4]