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  2. Lupus - Symptoms & causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/lupus

    The most distinctive sign of lupus — a facial rash that resembles the wings of a butterfly unfolding across both cheeks — occurs in many but not all cases of lupus. Some people are born with a tendency toward developing lupus, which may be triggered by infections, certain drugs or even sunlight.

  3. Sjogren's syndrome - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/sjogrens-syndrome/symptoms-causes/syc...

    Sjogren's (SHOW-grins) syndrome is a disorder of your immune system identified by its two most common symptoms — dry eyes and a dry mouth. The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus.

  4. Antiphospholipid syndrome - Symptoms & causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/antiphospholipid-syndrome/symptoms...

    Antiphospholipid syndrome is more common in women than in men. Having another autoimmune condition, such as lupus, increases the risk of antiphospholipid syndrome. It's possible to have the antibodies associated with antiphospholipid syndrome without developing signs or symptoms.

  5. Lupus nephritis - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/lupus-nephritis/symptoms-causes/syc...

    Signs and symptoms of lupus nephritis include: Blood in the urine. Urine that foams because of too much protein. High blood pressure. Swelling in the legs, ankles or feet and sometimes in the hands and face. High levels of a waste product called creatinine in the blood. Request an appointment.

  6. Lupus - Diagnosis & treatment - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/lupus/diagnosis-treatment/drc-20365790

    Signs and symptoms of lupus may change over time and overlap with those of many other disorders. No one test can diagnose lupus. The combination of blood and urine tests, signs and symptoms, and physical examination findings leads to the diagnosis.

  7. Ehlers-Danlos syndrome - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/ehlers-danlos-syndrome/symptoms-causes/...

    There are many different types of Ehlers-Danlos syndrome, but the most common signs and symptoms include: Overly flexible joints. Because the connective tissue that holds joints together is looser, your joints can move far past the normal range of motion. Joint pain and dislocations are common.

  8. Mixed connective tissue disease - Symptoms & causes - Mayo Clinic

    www.mayoclinic.org/.../symptoms-causes/syc-20375147

    Mixed connective tissue disease (MCTD) has signs and symptoms of a combination of disorders — primarily lupus, scleroderma, and polymyositis. Many people with this uncommon disease also have Sjogren's syndrome.

  9. Guillain-Barre syndrome - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/guillain-barre-syndrome/symptoms-causes/...

    Guillain-Barre (gee-YAH-buh-RAY) syndrome is a condition in which the body's immune system attacks the nerves. It can cause weakness, numbness or paralysis. Weakness and tingling in the hands and feet are usually the first symptoms. These sensations can quickly spread and may lead to paralysis.

  10. Raynaud's disease - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/raynauds-disease/symptoms-causes/syc...

    Symptoms of Raynaud's disease include: Cold fingers or toes. Areas of skin that turn white then blue. Depending on your skin color, these color changes may be harder or easier to see. Numb, prickly feeling or stinging pain upon warming or stress relief. During an attack of Raynaud's, affected areas of the skin usually first turn pale.

  11. Scleroderma - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/scleroderma

    Scleroderma is believed to be an autoimmune disease. This means that it occurs in part because the body's immune system begins to attack the connective tissues. People who have scleroderma also may have symptoms of another autoimmune disease such as rheumatoid arthritis, lupus or Sjogren syndrome. Complications