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  2. Respiratory compensation - Wikipedia

    en.wikipedia.org/wiki/Respiratory_compensation

    Hyperventilation due to the compensation for metabolic acidosis persists for 24 to 48 hours after correction of the acidosis, and can lead to respiratory alkalosis. [3] This compensation process can occur within minutes. [4] In metabolic alkalosis, chemoreceptors sense a deranged acid-base balance with a plasma pH of greater than normal (>7.4 ...

  3. Davenport diagram - Wikipedia

    en.wikipedia.org/wiki/Davenport_diagram

    Recall that the relationship represented in a Davenport diagram is a relationship between three variables: P CO 2, bicarbonate concentration and pH.Thus, Fig. 7 can be thought of as a topographical map—that is, a two-dimensional representation of a three-dimensional surface—where each isopleth indicates a different partial pressure or “altitude.”

  4. Respiratory alkalosis - Wikipedia

    en.wikipedia.org/wiki/Respiratory_alkalosis

    [1] [4] This condition is one of the four primary disturbances of acidbase homeostasis. [5] Respiratory compensation is also a condition where increased respiration reduces carbon dioxide sometimes to level below the normal range. In this case it is a physiological response to low pH from metabolic processes and not the primary disorder.

  5. Base excess - Wikipedia

    en.wikipedia.org/wiki/Base_excess

    Base excess is defined as the amount of strong acid that must be added to each liter of fully oxygenated blood to return the pH to 7.40 at a temperature of 37°C and a pCO 2 of 40 mmHg (5.3 kPa). [2] A base deficit (i.e., a negative base excess) can be correspondingly defined by the amount of strong base that must be added.

  6. Respiratory acidosis - Wikipedia

    en.wikipedia.org/wiki/Respiratory_acidosis

    Acute respiratory acidosis occurs when an abrupt failure of ventilation occurs. This failure in ventilation may be caused by depression of the central respiratory center by cerebral disease or drugs, inability to ventilate adequately due to neuromuscular disease (e.g., myasthenia gravis, amyotrophic lateral sclerosis, Guillain–Barré syndrome, muscular dystrophy), or airway obstruction ...

  7. Delta ratio - Wikipedia

    en.wikipedia.org/wiki/Delta_Ratio

    When this happens the numerator is large, the denominator is small, and the result is a delta ratio which is high (>2). This means a combined high anion gap metabolic acidosis and a pre-existing either respiratory acidosis or metabolic alkalosis (causing the high bicarbonate) – i.e. a mixed acidbase metabolic acidosis. [citation needed]

  8. Net acid excretion - Wikipedia

    en.wikipedia.org/wiki/Net_acid_excretion

    In renal physiology, net acid excretion (NAE) is the net amount of acid excreted in the urine per unit time. Its value depends on urine flow rate , urine acid concentration, and the concentration of bicarbonate in the urine (the loss of bicarbonate, a buffering agent , is physiologically equivalent to a gain in acid).

  9. Acid–base homeostasis - Wikipedia

    en.wikipedia.org/wiki/Acidbase_homeostasis

    An acid-base diagram for human plasma, showing the effects on the plasma pH when P CO 2 in mmHg or Standard Base Excess (SBE) occur in excess or are deficient in the plasma [23] Acidbase imbalance occurs when a significant insult causes the blood pH to shift out of the normal range (7.32 to 7.42 [16]).

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