Search results
Results from the WOW.Com Content Network
New research finds that millions of people on statins may not need to be taking the drugs. Researchers came to this conclusion after updating the method of assessing an individual’s 10-year risk ...
The small number of available trials do not support the use of statins as an adjunctive therapy or as a monotherapy in multiple sclerosis. [224] A modelling study in the UK found that people aged 70 and older who take statins live longer in good health than those who do not, regardless of whether they have cardiovascular disease. [225] [226]
Overall, our findings suggest that more people over 70 years of age should be considered for statin treatment.” — Borislava Mihaylova, DPhil “Cardiovascular disease remains a leading cause ...
A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after age 85. [2] Fibrates are indicated for hypertriglyceridemia. Fibrates typically lower triglycerides by 20% to 50%.
Risk factors for statin induced rhabdomyolysis include older age, renal impairment, high dose statins and use of medications that reduce the breakdown of statins (such as CYP3A4 inhibitors) or fibrates. [68] Persistent liver enzyme abnormalities (usually elevated in hepatic transaminases) have been documented. [69]
Most clinical trials evaluating statins have not included people 75 and older, and it’s been unclear if statins should be used in this age group. The findings suggest the medication can safely ...
[2] [3] They emphasize deprescribing medications that are unnecessary, which helps to reduce the problems of polypharmacy, drug interactions, and adverse drug reactions, thereby improving the risk–benefit ratio of medication regimens in at-risk people. [4] The criteria are used in geriatrics clinical care to monitor and improve the quality of ...
Aluminum and magnesium hydroxide antacids should not be taken within two hours of taking rosuvastatin [4] Coadministration of rosuvastatin with eluxadoline may increase the risk of rhabdomyolysis and myopathy [24] Grapefruit juice negatively interacts with several specific drugs in the statin class, but it has little or no effect on ...