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Though strep throat can be treated with antibiotics, untreated infections can turn dangerous quickly. ... to other parts of the body—such as the lungs, fat tissue, deep muscle, or blood ...
In addition, infection of GAS may lead to further complications and health conditions, namely acute rheumatic fever and poststreptococcal glomerulonephritis. Most common: impetigo, cellulitis, and erysipelas – infections of the skin which can be complicated by necrotizing fasciitis – skin, fascia and muscle; strep throat AKA strep ...
Streptolysin O is an oxygen-sensitive cytotoxin, secreted by most group A Streptococcus (GAS), and interacts with cholesterol in the membrane of eukaryotic cells (mainly red and white blood cells, macrophages, and platelets), and usually results in beta-hemolysis under the surface of blood agar. Streptolysin S is an oxygen-stable cytotoxin also ...
Underlying structural valve disease is usually present in patients before developing subacute endocarditis, and is less likely to lead to septic emboli than is acute endocarditis, but subacute endocarditis has a relatively slow process of infection and, if left untreated, can worsen for up to one year before it is fatal.
While a sore throat can be a side effect of many other illnesses, it's the most telling symptom of strep throat - contributing to more than 5 million physician visits a year in the United States ...
Left untreated, conditions causing persistent bacteremia can be potentially fatal. [ 17 ] Bacteremia is clinically distinct from sepsis , which is a condition where the blood stream infection is associated with an inflammatory response from the body, often causing abnormalities in body temperature , heart rate, breathing rate, blood pressure ...
Pain can be treated with paracetamol (acetaminophen) and nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen. [6] Strep throat is a common bacterial infection in children. [2] It is the cause of 15–40% of sore throats among children [7] [13] and 5–15% among adults. [8] Cases are more common in late winter and early spring. [13]
This invasion triggers the immune system to respond by sending white blood cells responsible for attacking microorganisms (neutrophils) to the lungs. The neutrophils engulf and kill the offending organisms but also release cytokines that result in a general activation of the immune system. This results in the fever, chills, and fatigue common ...