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Haloperidol is used in the treatment of schizophrenia, tics in Tourette syndrome, mania in bipolar disorder, delirium, agitation, acute psychosis, and hallucinations from alcohol withdrawal. [9][10][11] It may be used by mouth or injection into a muscle or a vein. [9] Haloperidol typically works within 30 to 60 minutes. [9]
Maropitant. Maropitant (INN; [ 2 ] brand name: Cerenia, used as maropitant citrate (USAN), is a neurokinin-1 (NK 1) receptor antagonist developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007, for use in dogs [ 3 ][ 4 ] and in 2012, for cats.
The human–canine bond is rooted in the domestication of the dog, which began occurring through their long-term association with hunter-gatherers more than 30,000–40,000 years ago. The earliest known relationship between dogs and humans is attested by the 1914 discovery of the Bonn–Oberkassel dog, who was buried alongside two humans in ...
Haloperidol decanoate is provided in the form of 50 or 100 mg/mL oil solution of sesame oil and benzyl alcohol in ampoules or pre-filled syringes. [6] [7] [9] Its elimination half-life after multiple doses is 21 days. [10] [11] The medication is marketed in many countries throughout the world. [3] [12
Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a treatment for depression and in pain management. [19] Ketamine is an NMDA receptor antagonist which accounts for most of its psychoactive effects. [20]
The use of antipsychotics may result in many unwanted side effects such as involuntary movement disorders, gynecomastia, impotence, weight gain and metabolic syndrome. Long-term use can produce adverse effects such as tardive dyskinesia, tardive dystonia, and tardive akathisia.
A dopamine antagonist, also known as an anti-dopaminergic and a dopamine receptor antagonist (DRA), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and as such they have found use in treating schizophrenia, bipolar disorder, and stimulant psychosis. [ 1 ]
The dog sense of smell is the most powerful sense of this species, the olfactory system of canines being much more complex and developed than that of humans. [ 1 ] It is believed to be up to 10 million times as sensitive as a human's in specialized breeds. Dogs have roughly forty times more smell-sensitive receptors than humans, ranging from ...
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