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About one in 10 people have restless leg syndrome, but the cause is a mystery. ... According to the Mayo Clinic, ... gabapentin enacarbil (Horizant) and pregabalin (Lyrica), may work for some ...
Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD). [13] [17] [18] Pregabalin also has antiallodynic properties.
Restless legs syndrome (RLS), (also known as Willis–Ekbom disease (WED), is a neurological disorder, usually chronic, that causes an overwhelming urge to move one's legs. [ 2 ] [ 10 ] There is often an unpleasant feeling in the legs that improves temporarily by moving them. [ 2 ]
Restless Legs Syndrome Awareness Day is Sept. 23. ... “Dopamine dysfunction is one of the key mechanisms currently believed to underlie restless legs syndrome, although work in this area is ...
More serious symptoms may also occur such as depersonalization, restless legs syndrome, seizures, and suicidal ideation. Benzodiazepine withdrawal can also lead to disturbances in mental function that persist for several months or years after onset of symptoms (referred to as post-acute-withdrawal syndrome in this form).
Heavy legs is a condition described as an unpleasant sensation of pain and heaviness in the lower limbs. Symptoms include legs feeling weighted, stiff, and tired. Heavy legs can be caused by a wide-ranging collection of disorders including but not restricted to varicose veins, peripheral artery disease, restless legs syndrome, multiple sclerosis, venous insufficiency.
Augmentation: [a] Especially when used to treat restless legs syndrome, long-term Pramipexole treatment may exhibit drug augmentation, which is "an iatrogenic worsening of RLS symptoms following treatment with dopaminergic agents" [24] and may include an earlier onset of symptoms during the day or a generalized increase in symptoms. [25] [26] [27]
Opioid withdrawal is a set of symptoms (a syndrome) arising from the sudden cessation or reduction of opioids where previous usage has been heavy and prolonged. [1] [2] Signs and symptoms of withdrawal can include drug craving, anxiety, restless legs syndrome, nausea, vomiting, diarrhea, sweating, and an elevated heart rate. Opioid use triggers ...
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