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  2. Glutethimide - Wikipedia

    en.wikipedia.org/wiki/Glutethimide

    Glutethimide is a hypnotic sedative that was introduced by Ciba [3] in 1954 as a safe alternative to barbiturates to treat insomnia. Before long, however, it had become clear that glutethimide was just as likely to cause addiction and caused similar withdrawal symptoms.

  3. List of Schedule II controlled substances (U.S.) - Wikipedia

    en.wikipedia.org/wiki/List_of_Schedule_II...

    This is the list of Schedule II controlled substances in the United States as defined by the Controlled Substances Act. [1] The following findings are required, by section 202 of that Act, for substances to be placed in this schedule:

  4. Aminoglutethimide - Wikipedia

    en.wikipedia.org/wiki/Aminoglutethimide

    Aminoglutethimide (AG), sold under the brand names Elipten, Cytadren, and Orimeten among others, is a medication which has been used in the treatment of seizures, Cushing's syndrome, breast cancer, and prostate cancer, among other indications.

  5. Depressant - Wikipedia

    en.wikipedia.org/wiki/Depressant

    Mixing codeine with glutethimide allowed more codeine to be converted into morphine in the body, thus increasing its effect. These were known as "hits", "cibas and codeine", and "dors and 4s". [citation needed] Glutethimide was believed to be safer than barbiturates, but many people died from the drug. Demand was high in the United States at ...

  6. Rogletimide - Wikipedia

    en.wikipedia.org/wiki/Rogletimide

    Rogletimide, also known as pyridoglutethimide, is a medication which was never marketed. [1] It is related in chemical structure to the sedative/hypnotic drug glutethimide, but instead has pharmacological activity as a selective aromatase inhibitor similar to the related drug aminoglutethimide and has no significant sedative-hypnotic effect. [2]

  7. Clomethiazole - Wikipedia

    en.wikipedia.org/wiki/Clomethiazole

    Clomethiazole is particularly toxic and dangerous if overdosed and is potentially fatal. Alcohol multiplies the effect. As the drug can be fatal in high doses, prescribing clomethiazole outside of a controlled environment, for example a hospital, is not recommended, especially because there are much less toxic alternatives, such as diazepam.

  8. Tasimelteon - Wikipedia

    en.wikipedia.org/wiki/Tasimelteon

    Tasimelteon, sold under the brand name Hetlioz, is a medication approved by the U.S. Food and Drug Administration (FDA) [3] in January 2014, for the treatment of non-24-hour sleep–wake disorder (also called non-24, N24 and N24HSWD). [4]

  9. Sodium oxybate - Wikipedia

    en.wikipedia.org/wiki/Sodium_oxybate

    The US label for sodium oxybate has a black box warning because it is a central nervous system depressant (CNS depressant) and for its potential for abuse.Other potential adverse side effects include respiratory depression, seizures, coma, and death, especially when it is taken in combination with other CNS depressants such as alcohol.