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A depot injection, also known as a long-acting injectable (LAI), is a term for an injection formulation of a medication which releases slowly over time to permit less ...
Lupron injection was approved by the FDA for treatment of advanced prostate cancer on 9 April 1985. [45] [4] [43] [44] Lupron depot for monthly intramuscular injection was approved by the FDA for palliative treatment of advanced prostate cancer on 26 January 1989. [8]
Depot MPA (DMPA) and EC/MPA were developed by Upjohn in the 1960s. [ 12 ] [ 13 ] DMPA (brand name Depo-Provera) was introduced for use as a progestogen-only injectable contraceptive for the first time outside of the United States in 1969 and was subsequently approved for use in birth control in the United States in 1992.
[38] [39] It is given by intramuscular or subcutaneous injection and forms a long-lasting depot, from which it is slowly released over a period of several months. It takes one week to take effect if given after the first five days of the period cycle, and is effective immediately if given during the first five days of the period cycle.
Medications and dosages used in transgender women [1] [2] [3] [4] [5] [a]; Medication Brand name Type Route Dosage [b]; Estradiol: Various: Estrogen: Oral: 2–10 mg ...
Estrogen levels after a single intramuscular injection of 10 mg estradiol valerate in oil in 24 postmenopausal women. [9] Determinations were made for both Progynon Depot 10 and Estradiol Depot 10, for a total of 48 measurements per point. [9] Assays were performed using GC/MS-NCI/SIM. [9] Source was Schug et al. (2012). [9]
There are two basic types of microinjection systems. The first is called a constant flow system and the second is called a pulsed flow system.In a constant flow system, which is relatively simple and inexpensive though clumsy and outdated, a constant flow of a sample is delivered from a micropipette and the amount of the sample which is injected is determined by how long the needle remains in ...
It has very low water solubility and forms a long-lasting microcrystalline depot within muscle upon intramuscular injection. [1] This repository slowly dissolves over time. [1] As a result, testosterone isobutyrate has a prolonged duration of action of approximately 2 weeks. [1] [2] [3] It is administered at intervals of once every 1 to 2 weeks ...
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