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Common side effects include headache, abdominal pain, diarrhea or constipation, and dizziness. [4] Serious side effects may include pneumonia and seizures. [4] [5] Use in pregnancy appears safe but has not been well studied, while use during breastfeeding is not recommended. [1] Famotidine was patented in 1979 and came into medical use in 1985. [6]
Ranitidine has 10% of the affinity that cimetidine has to CYP450, so it causes fewer side effects, but other H 2 blockers famotidine and nizatidine have no CYP450 significant interactions. [131] Ranitidine was introduced in 1981, and was the world's biggest-selling prescription drug by 1987. [132]
Ranitidine is not as potent a CYP inhibitor as cimetidine, although it still shares several of the latter's interactions (such as with warfarin, theophylline, phenytoin, metoprolol, and midazolam). [21] Famotidine has negligible effect on the CYP system, and appears to have no significant interactions. [20]
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(Reuters) -A Delaware judge has allowed more than 70,000 lawsuits over discontinued heartburn drug Zantac to go forward, ruling that expert witnesses can testify in court that the drug may cause ...
Some tests showed that Zantac's active ingredient, ranitidine, could degrade into NDMA over time or when exposed to heat. The U.S. Food and Drug Administration asked manufacturers to pull the drug ...
Zantac can refer to either of two different H 2 antagonists used to reduce gastric acid secretion: Ranitidine , prior to its 2020 withdrawal from the market Famotidine , following the withdrawal of ranitidine
Lighter Side. Politics. Science & Tech. Sports. Weather. 24/7 Help. For premium support please call: 800-290-4726 more ways to reach us. Sign in. Mail. ... Zantac 360, is made with famotidine, a ...
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