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  2. E/A ratio - Wikipedia

    en.wikipedia.org/wiki/E/A_ratio

    From this, a number of grades of diastolic function can be determined: [citation needed] Normal diastolic function (E > A) Impaired relaxation (E:A reversal i.e., E is < A) Pseudonormal (E:A ratio appears normal) Restrictive filling (E:A ratio often > 2) Pseudonormalisation shows a transmitral profile that appears normal.

  3. Diastolic function - Wikipedia

    en.wikipedia.org/wiki/Diastolic_function

    In clinical cardiology the term "diastolic function" is most commonly referred as how the heart fills. [1] Parallel to "diastolic function", the term " systolic function" is usually referenced in terms of the left ventricular ejection fraction (LVEF), which is the ratio of stroke volume and end-diastolic volume . [ 2 ]

  4. Heart failure with preserved ejection fraction - Wikipedia

    en.wikipedia.org/wiki/Heart_failure_with...

    Heart failure with preserved ejection fraction (HFpEF) is a form of heart failure in which the ejection fraction – the percentage of the volume of blood ejected from the left ventricle with each heartbeat divided by the volume of blood when the left ventricle is maximally filled – is normal, defined as greater than 50%; [1] this may be measured by echocardiography or cardiac catheterization.

  5. Isovolumic relaxation time - Wikipedia

    en.wikipedia.org/wiki/Isovolumic_relaxation_time

    Wiggers diagram of the cardiac cycle, with isovolumic relaxation marked at top. Isovolumic relaxation time (IVRT) is an interval in the cardiac cycle, from the aortic component of the second heart sound, that is, closure of the aortic valve, to onset of filling by opening of the mitral valve. [1] It can be used as an indicator of diastolic ...

  6. Diastole - Wikipedia

    en.wikipedia.org/wiki/Diastole

    Effects of impaired diastolic function [ edit ] Brain natriuretic peptide (BNP) is a cardiac neurohormone secreted from ventricular myocytes (ventricular muscle cells) at the end of diastole—this in response to the normal, or sub-normal (as the case may be), stretching of cardiomyocytes (heart muscle cells) during systole.

  7. Ejection fraction - Wikipedia

    en.wikipedia.org/wiki/Ejection_fraction

    Modalities applied to measurement of ejection fraction is an emerging field of medical mathematics and subsequent computational applications. The first common measurement method is echocardiography, [7] [8] although cardiac magnetic resonance imaging (MRI), [8] [9] cardiac computed tomography, [8] [9] ventriculography and nuclear medicine (gated SPECT and radionuclide angiography) [8] [10 ...

  8. Diabetic cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Diabetic_cardiomyopathy

    Defects in cellular processes such as autophagy and mitophagy are thought to contribute to the development of diabetic cardiomyopathy. [2] Diabetic cardiomyopathy is characterized functionally by ventricular dilation, enlargement of heart cells, prominent interstitial fibrosis and decreased or preserved systolic function [5] in the presence of a diastolic dysfunction.

  9. Wiggers diagram - Wikipedia

    en.wikipedia.org/wiki/Wiggers_diagram

    A Wiggers diagram modified from [1]. A Wiggers diagram, named after its developer, Carl Wiggers, is a unique diagram that has been used in teaching cardiac physiology for more than a century.

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