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Anesthetic machine, showing sevoflurane (yellow) and isoflurane (purple) vaporizers on the right. An anesthetic vaporizer (American English) or anaesthetic vapouriser (British English) is a device generally attached to an anesthetic machine which delivers a given concentration of a volatile anesthetic agent. It works by controlling the ...
General anesthesia does not always require the anesthetic machine, tested daily, as basic equipment. Anesthesia machines may differ in appearance, size and degree of sophistication but generally speaking, they consist of sections for: ventilation; Peripheral Nerve Stimulator; space for monitoring equipment; accessories; storage space; worktop
Minimum alveolar concentration or MAC is the concentration, often expressed as a percentage by volume, of a vapour in the alveoli of the lungs that is needed to prevent movement (motor response) in 50% of subjects in response to surgical (pain) stimulus.
The full mechanism of action of volatile anaesthetic agents is unknown and has been the subject of intense debate. "Anesthetics have been used for 160 years, and how they work is one of the great mysteries of neuroscience," says anaesthesiologist James Sonner of the University of California , San Francisco.
Sevoflurane is an inhaled anesthetic that is often used to induce and maintain anesthesia in children for surgery. [17] During the process of awakening from the medication, it has been associated with a high incidence (>30%) of agitation and delirium in preschool children undergoing minor noninvasive surgery. [ 17 ]
To determine the depth of anesthesia, the anesthetist relies on a series of physical signs of the patient. In 1847, John Snow (1813–1858) [ 1 ] and Francis Plomley [ 2 ] attempted to describe various stages of general anesthesia, but Guedel in 1937 described a detailed system which was generally accepted.
The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.
Balanced anesthesia, also known as multimodal anesthesia (also spelt: anaesthesia), is a technique used to induce and maintain anesthesia in patients undergoing surgery or certain medical procedures.