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Many patients will not develop these side effects, although there is still a significant possibility of risks associated with Antipsychotic usage. The percentage of patients affected by side effects like Tardive dyskinesia is significantly high and estimated to be a 20-50% prevalence. [1] [2]
Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.
Carbamazepine, sold under the brand name Tegretol among others, is an anticonvulsant medication used in the treatment of epilepsy and neuropathic pain. [4] [1] It is used as an adjunctive treatment in schizophrenia along with other medications and as a second-line agent in bipolar disorder.
Elderly people are also at a heightened risk for developing TD, [10] as are females and those with organic brain injuries or diabetes mellitus and those with the negative symptoms of schizophrenia. [25] TD is also more common in those that experience acute neurological side effects from antipsychotic drug treatment. [25]
Olanzapine, sold under the brand name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder. [13] It is also sometimes used off-label for treatment of chemotherapy-induced nausea and vomiting [14] and as an appetite stimulant. [15]
Weight loss, a possible treatment for opioid use disorder, and reduced risks for heart disease, stroke, and a slew of other diseases—those are just some of the benefits of Ozempic, the type 2 ...
Anticholinergics generally have antisialagogue effects (decreasing saliva production), and most produce some level of sedation, both being advantageous in surgical procedures. [ 8 ] [ 9 ] Until the beginning of the 20th century, anticholinergic drugs were widely used to treat psychiatric disorders.
Hepatotoxicity, dermatological side effects, and abuse potential. [7] Aminopyrine: 1999 France, Thailand Risk of agranulocytosis and severe acne. [3] Amobarbital: 1980 Norway Risk of barbiturate toxicity. [3] Amoproxan: 1970 France Dermatologic and ophthalmic toxicity. [3] Anagestone acetate: 1969 Germany Animal carcinogenicity. [3] Antrafenine ...