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Current research in molecular imaging involves cellular/molecular biology, chemistry, and medical physics, and is focused on: 1) developing imaging methods to detect previously undetectable types of molecules, 2) expanding the number and types of contrast agents available, and 3) developing functional contrast agents that provide information ...
Molecular Imaging and Biology is published by Springer Science+Business Media as the official journal of the World Molecular Imaging Society (WMIS) in collaboration with the European Society for Molecular Imaging (ESMI). It publishes original research contributions on the utilization of molecular imaging in problems of relevance to biology and ...
In biology, a probe is a single strand of DNA or RNA that is complementary to a nucleotide sequence of interest. RNA probes can be designed for any gene or any sequence within a gene for visualization of mRNA , [ 3 ] [ 4 ] [ 5 ] lncRNA [ 6 ] [ 7 ] [ 8 ] and miRNA in tissues and cells.
Biological imaging may refer to any imaging technique used in biology. Typical examples include: Bioluminescence imaging, a technique for studying laboratory animals using luminescent protein; Calcium imaging, determining the calcium status of a tissue using fluorescent light
A simplified Jablonski diagram illustrating the change of energy levels.. The principle behind fluorescence is that the fluorescent moiety contains electrons which can absorb a photon and briefly enter an excited state before either dispersing the energy non-radiatively or emitting it as a photon, but with a lower energy, i.e., at a longer wavelength (wavelength and energy are inversely ...
Bioimage informatics is a subfield of bioinformatics and computational biology. [1] It focuses on the use of computational techniques to analyze bioimages, especially cellular and molecular images, at large scale and high throughput. The goal is to obtain useful knowledge out of complicated and heterogeneous image and related metadata.
Live-cell imaging is the study of living cells using time-lapse microscopy. It is used by scientists to obtain a better understanding of biological function through the study of cellular dynamics. [1] Live-cell imaging was pioneered in the first decade of the 21st century.
In this specific context, molecular, biological, and pre-clinical imaging render additional data and understanding of basic structure and function in molecules, cells, tissues and animal models that may be transferred to human physiology where appropriate. The applications of image-based VPH/Physiome models in basic and clinical domains are vast.