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Phenylephrine is a selective α 1 -adrenergic receptor agonist with minimal to no β-adrenergic receptor agonist activity or induction of norepinephrine release. [ 5 ][ 8 ][ 15 ] It causes constriction of both arteries and veins. [ 12 ] Phenylephrine was patented in 1933 [ 16 ] and came into medical use in 1938. [ 17 ]
“There’s so many other products out there that really do work,” Dr. James Tracy, vice president of the American College of Allergy, Asthma and Immunology, previously told Yahoo Life.
Pseudoephedrine, sold under the brand name Sudafedamong others, is a sympathomimeticmedicationwhich is used as a decongestantto treat nasal congestion. [1][13][2]It has also been used off-labelfor certain other indications, like treatment of low blood pressure.
H1 antagonists, also called H1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions. Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic action but are ...
Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. [ 1 ] Antihistamines are usually for short-term treatment. [ 1 ]
Allergic rhinitis, of which the seasonal type is called hay fever, is a type of inflammation in the nose that occurs when the immune system overreacts to allergens in the air. [6] Signs and symptoms include a runny or stuffy nose, sneezing, red, itchy, and watery eyes, and swelling around the eyes. [1] The fluid from the nose is usually clear. [2]
Advisers to the Food and Drug Administration voted unanimously on Tuesday against the effectiveness of the key drug found in popular versions of Sudafed, Dayquil and other medications stocked on ...
Cetirizine/pseudoephedrine (Zyrtec-D) is an antihistamine and decongestant formulation. It is a fixed-dose combination drug containing 5 mg cetirizine hydrochloride and 120 mg pseudoephedrine hydrochloride for symptoms related to seasonal allergic rhinitis. [1][2][3] Cetirizine/pseudoephedrine gained approval from the U.S. Food and Drug ...
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