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Plummer–Vinson syndrome (also known as Paterson–Kelly syndrome [1] or Paterson–Brown-Kelly syndrome in the UK [2]) is a rare disease characterized by dysphagia (difficulty swallowing), iron-deficiency anemia, glossitis (inflammation of the tongue), cheilosis (cracking at the corners of the mouth), and esophageal webs (thin membranes in the esophagus that can cause obstruction). [1]
Iron-deficiency anemia is mainly caused by blood loss, such as may occur during menses or gastrointestinal hemorrhage.This often results in a depapilled, atrophic glossitis, giving the tongue a bald and shiny appearance, along with pallor (paleness) of the lips and other mucous membranes a tendency towards recurrent oral ulceration, [6] and cheilosis (swelling of the lips). [7]
The diagnosis of a people with a burning symptom may also involve psychologic screening e.g. depression questionnaires. [1] The second edition of the International Classification of Headache Disorders lists diagnostic criteria for "Glossodynia and Sore Mouth": A. Pain in the mouth present daily and persisting for most of the day,
ICD-10 coding number Diseases Database coding number Medical Subject Headings Iron-deficiency anemia: D50: 6947: Iron-deficiency anemia (or iron deficiency anaemia) is a common anemia that occurs when iron loss (often from intestinal bleeding or menses) occurs, and/or the dietary intake or absorption of iron is insufficient. In such a state ...
54,200 (2015) [ 7 ] Iron-deficiency anemia is anemia caused by a lack of iron. [ 3 ] Anemia is defined as a decrease in the number of red blood cells or the amount of hemoglobin in the blood. [ 3 ] When onset is slow, symptoms are often vague such as feeling tired, weak, short of breath, or having decreased ability to exercise. [ 1 ]
Adult-onset Still's disease (AOSD) is a form of Still's disease, a rare systemic autoinflammatory disease characterized by the classic triad of fevers, joint pain, and a distinctive salmon-colored bumpy rash. The disease is considered a diagnosis of exclusion. [1] Levels of the iron-binding protein ferritin may be extremely elevated with this ...
Frequency. 1 per 1000 people [ 8 ] Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [ 5 ] Those affected often have a gradual onset. [ 5 ] The most common initial symptoms are feeling tired and weak. [ 4 ]
Tongue lesions are very common. For example, in the United States one estimated point prevalence was 15.5% in adults. [10] Tongue lesions are more common in persons who wear dentures and tobacco users. [10] The most common tongue conditions are geographic tongue, followed by fissured tongue and hairy tongue. [10]