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An osteocyte, an oblate shaped type of bone cellwith dendritic processes, is the most commonly found cellin mature bone. It can live as long as the organism itself.[1] The adult human body has about 42 billion of them.[2] Osteocytes do not divide and have an average half life of 25 years. They are derived from osteoprogenitor cells, some of ...
Cancellous bone or spongy bone, [12] [11] also known as trabecular bone, is the internal tissue of the skeletal bone and is an open cell porous network that follows the material properties of biofoams. [13] [14] Cancellous bone has a higher surface-area-to-volume ratio than cortical bone and it is less dense. This makes it weaker and more flexible.
Osteoblasts (from the Greek combining forms for "bone", ὀστέο-, osteo- and βλαστάνω, blastanō "germinate") are cells with a single nucleus that synthesize bone. However, in the process of bone formation, osteoblasts function in groups of connected cells. Individual cells cannot make bone.
An osteoclast (from Ancient Greek ὀστέον (osteon) 'bone' and κλαστός (clastos) 'broken') is a type of bone cell that breaks down bone tissue. This function is critical in the maintenance, repair, and remodeling of bones of the vertebral skeleton. The osteoclast disassembles and digests the composite of hydrated protein and mineral ...
Diagram of a typical long bone showing both compact (cortical) and cancellous (spongy) bone. In osteology, the osteon or haversian system (/ həˈvɜːr.ʒən /; named for Clopton Havers) is the fundamental functional unit of much compact bone. Osteons are roughly cylindrical structures that are typically between 0.25 mm and 0.35 mm in diameter ...
Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. [ 2 ] In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). [ 3 ] It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells.
The human skeleton is the internal framework of the human body. It is composed of around 270 bones at birth – this total decreases to around 206 bones by adulthood after some bones get fused together. [ 1 ] The bone mass in the skeleton makes up about 14% of the total body weight (ca. 10–11 kg for an average person) and reaches maximum mass ...
Osteopontin (OPN), also known as bone /sialoprotein I (BSP-1 or BNSP), early T-lymphocyte activation (ETA-1), secreted phosphoprotein 1 (SPP1), 2ar and Rickettsia resistance (Ric), [ 5 ] is a protein that in humans is encoded by the SPP1 gene (secreted phosphoprotein 1). The murine ortholog is Spp1. Osteopontin is a SIBLING (glycoprotein) that ...