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Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
This vaccine is the first to meet the World Health Organization's Malaria Vaccine Technology Roadmap goal of a vaccine with at least 75% efficacy. [145] Germany-based BioNTECH SE is developing an mRNA-based malaria vaccine BN165 [146] which has recently initiated a Phase 1 study [clinicaltrials.gov identifier: NCT05581641] in December 2022. The ...
The most effective malaria vaccine is the R21/Matrix-M, with a 77% efficacy rate shown in initial trials and significantly higher antibody levels than with the RTS,S vaccine. It is the first vaccine that meets the World Health Organization's (WHO) goal of a malaria vaccine with at least 75% efficacy, [6] [7] and only the second malaria vaccine ...
The World Health Organization has prequalified a new dengue vaccine recommended for use in children in areas where mosquito transmission to humans is high.
A new vaccine candidate was more than 83 percent effective at protecting against hospitalizations over a three-year clinical trial. Dengue virus is a mosquito-borne disease that can cause severe ...
Two types of dengue vaccine have been approved and are commercially available. Dengvaxia became available in 2016, but it is only recommended to prevent re-infection in individuals who have been previously infected. [13] The second vaccine, Qdenga, became available in 2022 and is suitable for adults, adolescents and children from four years of ...
In May 2024, TAK-003 became the second dengue vaccine to be prequalified by the World Health Organization (WHO). [51] This live-attenuated vaccine, developed by Takeda is similar to the Dengvaxia vaccine in the fact that it contains a weakened version of the four variants of dengue virus. The difference between the two vaccines is the TAK-003 ...
For example, the human body louse transmits the bacterium Rickettsia prowazekii which causes epidemic typhus. Although invertebrate-transmitted diseases pose a particular threat on the continents of Africa, Asia and South America, there is one way of controlling invertebrate-borne diseases, which is by controlling the invertebrate vector.