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The origins of pathophysiology as a distinct field date back to the late 18th century. The first known lectures on the subject were delivered by Professor August Friedrich Hecker at the University of Erfurt in 1790, and in 1791, he published the first textbook on pathophysiology, Grundriss der Physiologia pathologica, [2] spanning 770 pages. [3]
In DIC, the processes of coagulation and fibrinolysis are dysregulated, and the result is widespread clotting with resultant bleeding. Regardless of the triggering event of DIC, once initiated, the pathophysiology of DIC is similar in all conditions. One critical mediator of DIC is the release of a transmembrane glycoprotein called tissue ...
Systemic alterations resulting from a variety of disease states are explored. Specific emphasis is placed on etiology, pathogenesis, environmental influences, and clinical manifestations of common alterations across the lifespan. Students will edit chosen articles on Wikipedia that are applicable to pathophysiology and of interest to the student.
Guillain–Barré syndrome (also called "GBS") is a rapid-onset muscle weakness caused by the immune system damaging the peripheral nervous system. [3] Typically, both sides of the body are involved, and the initial symptoms are changes in sensation or pain often in the back along with muscle weakness, beginning in the feet and hands, often spreading to the arms and upper body. [3]
Prior to World War I, there were several competing hypotheses behind the pathophysiology of shock. Of the various theories, the most well regarded was a theory penned by George W. Crile who suggested in his 1899 monograph, " An Experimental Research into Surgical Shock" , that shock was quintessentially defined as a state of circulatory ...
The first known description of Mordake is found in an 1895 article in The Boston Post authored by fiction writer Charles Lotin Hildreth. [7] The article describes a number of cases of what Hildreth refers to as "human freaks", including a woman who had the tail of a fish, a man with the body of a spider, a man who was half-crab, and Edward Mordake.
A Certificate of Advanced Study (CAS), [1] also called an Advanced Certificate (AC), [2] [3] [4] Certificate of Advanced Graduate Study (CAGS), [5] or a Certificate of Advanced Professional Studies (CAPS), is a post-Master's academic certificate designed for professional and non traditional students, as well as practitioners who seek a continuing education program to enhance their professional ...
The pathophysiology of autoimmune thyroiditis is not well understood. [5] However, once the disease is established, its core processes have been observed: Hashimoto's Thyroiditis is a T-lymphocyte mediated attack on the thyroid gland. [ 15 ]