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Lipedema is a condition that is almost exclusively found in women [3] and results in enlargement of both legs due to deposits of fat under the skin. [2] Women of any weight may be affected [ 2 ] [ 3 ] and the fat is resistant to traditional weight-loss methods. [ 4 ]
Vastly more women than men have the condition, which causes accumulation of unusual deposits of adipose tissue predominately in the legs and arms, according to the Lipedema Foundation. According ...
Dercum's disease is a rare condition characterized by multiple painful fatty tumors, called lipomas, that can grow anywhere in subcutaneous fat across the body. [1] Sometimes referred as adiposis dolorosa in medical literature, Dercum’s disease is more of a syndrome than a disease (because it has several clinically recognizable features, signs, and symptoms that are characteristic of it and ...
Adiposis dolorosa is an outdated term for many years used synonymously as Dercum's disease, lipedema or Anders disease. [1] While there are numerous references to adiposis dolorosa, it is recommended that the term no longer be used. Dercum's is now recognized as a separate condition, as is lipedema. [2] [3]
The exact cause of this condition is not known, but it involves collagen degeneration and a granulomatous response in the layer of the skin called the dermis, often affecting the deeper fat layer and thickening dermal blood vessels. Diagnosis is confirmed through a skin biopsy showing inflammatory cell infiltrate and necrotising vasculitis.
In women, it is most prevalent in an upper limb after breast cancer surgery, especially axillary lymph node dissection, [15] and occurs on the same side of the body as the surgery. Breast and trunk lymphedema can also occur but go unrecognised as there is swelling in the area after surgery, and its symptoms ( peau d'orange and an inverted ...
Inflammatory arthritis can sometimes cause symptoms in parts of the body other than the joints, like the eyes, heart, or lungs. As arthritis progresses, joint damage can get worse.
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