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Prednisolone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is the 21-acetate ester of prednisolone. [1] [2] Safety.
Prednicarbate (prednisolone 17-(ethyl carbonate) 21-propionate) Prednimustine (prednisolone chlorambucil ester) Prednisolamate (prednisolone diethylaminoacetate) Prednisolone acetate; Prednisolone hexanoate; Prednisolone metasulphobenzoate (prednisolone 21-(3-sulfobenzoate)) Prednisolone palmitate; Prednisolone phosphate; Prednisolone ...
In horses, prednisolone acetate suspensions are priorly used to treat inflammation in the middle layer of the eye, also known as anterior uveitis and equine recurrent uveitis (ERU), which is the leading cause of visual impairment in horses. [58] Prednisolone acetate eye drops are not to be used in other animals such as birds. [57]
Methylprednisolone acetate suspension (Depo-Medrol) is a 6-methyl derivative of prednisolone that melts at 215 degrees Celsius with some decomposition. [23] Methylprednisolone sodium succinate (Solu-Medrol) is the sodium succinate ester of methylprednisolone.
Cortisone is a pregnene (21-carbon) steroid hormone.It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug. Cortisol is converted by the action of the enzyme corticosteroid 11-beta-dehydrogenase isozyme 2 into the inactive metabolite cortisone, particularly in the kidneys.
[1] [4] [5] Methylprednisolone acetate was previously suspended with polyethylene glycol but is no longer formulated with this excipient due to concerns about possible toxicity. [6] [8] Depo methylprednisolone acetate is a depot injection and is absorbed slowly with a duration of weeks to months with a single intramuscular injection. [5]