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Upon the original patent expiration, Hi-Tech Pharma was the first of many generic competitors to submit an abbreviated new drug application (ANDA) for dorzolamide hydrochloride/timolol maleate eye drops. [19] Hi-Tech Pharma's ANDA was approved on 28 October 2008. At the time, controversy surrounded the approval of this first ANDA.
It is used as an eye drop. [3] Effects begin within three hours and last for at least eight hours. [3] It is also available as the combination dorzolamide/timolol. [3] [4] Common side effects include eye discomfort, eye redness, taste changes, and blurry vision. [3] Serious side effects include Steven Johnson syndrome. [3]
Cyclopentolate, Atropine, Tropicamide, and Homatropine are the typical cycloplegic eye drops used once daily to treat spasm of accommodation by relaxing the ciliary muscle. One side effect is blurred vision since these induce dilation.
The FDA recently cautioned against using dozens of kinds of eyedrops — its third warning this year — leading to some wondering whether any drops are safe to use. Eye doctors weigh in.
An outer layer of the eye, called the corneal dome, does not have blood vessels that are usually critical in the immune system process because the eye “has to maintain a crystal clarity ...
Specifically it is used to help examine the back of the eye. [4] It is applied as eye drops. [3] Effects occur within 40 minutes and last for up to a day. [3] Common side effects include blurry vision, increased intraocular pressure, and sensitivity to light. [3] Another rare but severe side effect is psychosis, particularly in children. [3]
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