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Alcohol and some drugs can also cause breast enlargement. [4] [7] Other causes may include Klinefelter syndrome, metabolic dysfunction, or a natural decline in testosterone production. [4] [6] [8] This may occur even if the levels of estrogens and androgens are both appropriate, but the ratio is altered. [7]
Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.
Aromatase (EC 1.14.14.14), also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is CYP19A1 , a member of the cytochrome P450 superfamily, which are monooxygenases that catalyze many reactions involved in steroidogenesis .
Menopause belly is weight gain in the midsection due to hormonal changes. But MDs have advice for treating and preventing it in perimenopause and menopause.
Studies have shown high levels are at least partially to blame for premenstrual syndrome, endometriosis, fibroids and even breast cancer. To top it off, as estrogen levels decline, women gain ...
Liver cirrhosis is another cause, though through lowered metabolism of estrogen, not oversecretion or overconsumption like the aforementioned. It's necessary to know there exist two kinds of hyperestrogenism: Absolute (more concentration than usual of estrogen) and relative (a normal concentration of estrogen, higher with respect to progesterone).
An additional benefit to exercising is that it reduces stress and insulin levels, which reduce the presence of cortisol, a hormone that leads to more belly fat deposits and leptin resistance. [114] Self-motivation by understanding the risks associated with abdominal obesity is widely regarded as being far more important than worries about ...
Estrogen insensitivity syndrome (EIS), or estrogen resistance, is a form of congenital estrogen deficiency or hypoestrogenism [2] which is caused by a defective estrogen receptor (ER) – specifically, the estrogen receptor alpha (ERα) – that results in an inability of estrogen to mediate its biological effects in the body. [3]