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Increased blood pressure in the veins (venous hypertension) can cause diffusion of substances, including fibrin, out of capillaries. Fibrotic tissue may predispose the tissue to ulceration. Recurrent ulceration and fat necrosis is associated with lipodermatosclerosis. In advanced lipodermatosclerosis the proximal leg swells from chronic venous ...
Lipomas have a prevalence of roughly 2 out of every 100 people. [2] Lipomas typically occur in adults between 40 and 60 years of age. [1] Males are more often affected than females. [1] They are the most common noncancerous soft-tissue tumor. [5] The first use of the term "lipoma" to describe these tumors was in 1709. [6]
The bumps are caused by pressure. [1] There may be an association with Prader–Willi syndrome , and around a third of individuals with Ehlers–Danlos syndrome may have them. [ 2 ] Risk factors include obesity , flat feet , athletics , figure skating , and long-distance running .
Nodules are small firm lumps usually greater than 1 cm in diameter, found in skin and other organs. [ 1 ] [ 2 ] If filled with fluid they are usually softer and referred to as cysts . [ 2 ] Smaller (less than 0.5 cm) raised soft tissue bumps may be termed papules .
A dermatofibroma, or benign fibrous histiocytomas, is a benign nodule in the skin, typically on the legs, elbows or chest of an adult. [3] It is usually painless. [3] It usually ranges from 0.2cm to 2cm in size but larger examples have been reported. [3] It typically results from mild trauma such as an insect bite. [3]
AFST tumors commonly present as slowly growing, painless, deep-seated lumps in individuals aged 6 to 86 years old (median age 47-50 years in different studies). [4] The tumors are most common in the lower extremities but uncommonly occur in the back, chest wall, iliac crest, groin and nearby lower lateral abdominal region, [4] abdominal cavity, pelvic cavity, [5] breast, [3] cheek, temporal ...
the 'typical' ulcerative form, which occurs in the legs; an 'atypical' form that is more superficial and occurs in the hands and other parts of the body; Other variations are: [4] Peristomal pyoderma gangrenosum comprises 15% of all cases of pyoderma; Bullous pyoderma gangrenosum; Pustular pyoderma gangrenosum [5] Vegetative pyoderma ...
[2] [13] Symptoms and signs usually result from the pressure effect of the tumor. [1] There may be a lump, with or without pain. [1] Pain may increase with the growth of the tumor and may be worse at night and at rest. [1] [3] A bone tumor might present with an unexplained broken bone; with little or no trauma. [2]