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DMARDs also act to relieve pain and decrease progression and worsening of RA. It mainly functions by slowing or stopping the immune system from attacking the joints. [9] Conventional DMARDs are known to be the first-line treatment for rheumatoid arthritis. [9] Treatment can be a monotherapy or in combination with other anti-arthritic medications.
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Magnesium salicylate is a common analgesic [1] and nonsteroidal anti-inflammatory drug (NSAID) [2] used to treat mild to moderate musculoskeletal pain [3] such as in tendons and muscles. [citation needed] It is also used to treat joint pain like arthritis, [2] [3] general back pain, [4] and headaches. [citation needed]
The goals of treatment are to reduce pain, decrease inflammation, and improve a person's overall functioning. [5] This may be helped by balancing rest and exercise, the use of splints and braces, or the use of assistive devices. [1] [6] [7] Pain medications, steroids, and NSAIDs are frequently used to help with symptoms. [1]
The pain medication paracetamol (acetaminophen) is the first line treatment for osteoarthritis. [ 61 ] [ 95 ] Pain relief does not differ according to dosage. [ 62 ] However, a 2015 review found acetaminophen to have only a small short-term benefit with some concerns on abnormal results for liver function test . [ 96 ]
The exact medications recommended will vary by country and the individual treatment center, but the following gives an example of the WHO approach to treating chronic pain with medications. If, at any point, treatment fails to provide adequate pain relief, then the doctor and patient move onto the next step.
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