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Muehrcke's lines were described by American physician Robert C. Muehrcke (1921–2003) in 1956. In a study published in BMJ, he examined patients with known chronic hypoalbuminemia and healthy volunteers, finding that the appearance of multiple transverse white lines was a highly specific marker for low serum albumin (no subject with the sign had SA over 2.2 g/dL), was associated with severity ...
Mees' lines can look similar to injury to the nail, which should not be confused with true Mees' lines. [1] Mees' lines appear after an episode of poisoning with arsenic, [2] thallium or other heavy metals or selenium, [3] opioid MT-45, and can also appear if the subject is suffering from kidney failure. [4] They have been observed in ...
Leukonychia striata, transverse leukonychia, or Mees' lines are a whitening or discoloration of the nail in bands or "stria" that run parallel to the lunula (nail base). This is commonly caused by physical injury or disruption of the nail matrix.
While Beau's lines are actual ridges and indentations in the nail plate, Muehrcke lines are areas of hypopigmentation without palpable ridges; they affect the underlying nail bed, and not the nail itself. Beau's lines should also be distinguished from Mees' lines of the fingernails, which are areas of discoloration in the nail plate.
White lines across the nail (leukonychia striata, or transverse leukonychia) may be Mees' lines or Muehrcke's lines. Small white patches are known as leukonychia punctata. Dark nails are associated with B 12 deficiency. Stains of the nail plate (not the nail bed) are associated with smoking and henna use.
Onychomadesis is defined by the nail plate's detachment from the matrix, its continuous connection to the nail bed, and, frequently but not always, shedding. [4] Beau lines are transverse ridges on the nail plates. [5]
Growing older or having poor biomechanics, which are more common in the elderly (e.g., toes that overlap and underlap; incompatibility between the foot and the shoe; or digiti flexi, which is characterized by contracted toes due to toe buckling caused by shortening of the controlling muscles), may be contributing factors.
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