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  2. DNA methylation - Wikipedia

    en.wikipedia.org/wiki/DNA_methylation

    DNA methylation appears absolutely required in differentiated cells, as knockout of any of the three competent DNA methyltransferase results in embryonic or post-partum lethality. By contrast, DNA methylation is dispensable in undifferentiated cell types, such as the inner cell mass of the blastocyst, primordial germ cells or embryonic stem cells.

  3. Epigenome - Wikipedia

    en.wikipedia.org/wiki/Epigenome

    The function of DNA strands (yellow) alters depending on how it is organized around histones (blue) that can be methylated (green).. In biology, the epigenome of an organism is the collection of chemical changes to its DNA and histone proteins that affects when, where, and how the DNA is expressed; these changes can be passed down to an organism's offspring via transgenerational epigenetic ...

  4. Contribution of epigenetic modifications to evolution - Wikipedia

    en.wikipedia.org/wiki/Contribution_of_epigenetic...

    DNA methylation can be stable during cell division, allowing for methylation states to be passed to other orthologous genes in a genome. DNA methylation can be reversed via enzymes known as DNA de-methylases, while histone modifications can be reversed by removing histone acetyl groups with deacetylases. The process of DNA methylation reversal ...

  5. Genomic imprinting - Wikipedia

    en.wikipedia.org/wiki/Genomic_imprinting

    It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established ("imprinted") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.

  6. Transgenerational epigenetic inheritance - Wikipedia

    en.wikipedia.org/wiki/Transgenerational...

    However, some epigenetic marks, particularly maternal DNA methylation, can escape this reprogramming; leading to parental imprinting. [citation needed] In the primordial germ cells (PGC) there is a more extensive erasure of epigenetic information. However, some rare sites can also evade erasure of DNA methylation. [29]

  7. Epigenetics - Wikipedia

    en.wikipedia.org/wiki/Epigenetics

    Epigenetic mechanisms. In biology, epigenetics is the study of heritable traits, or a stable change of cell function, that happen without changes to the DNA sequence. [1] The Greek prefix epi-(ἐπι-"over, outside of, around") in epigenetics implies features that are "on top of" or "in addition to" the traditional (DNA sequence based) genetic mechanism of inheritance. [2]

  8. Does the Formula of “The Simple Life” Still Hold Up?

    www.aol.com/does-formula-simple-life-still...

    Today’s reality TV wouldn’t exist without The Simple Life. The original series, which starred a then 20-something Paris Hilton and Nicole Richie navigating small-town life, is one of the ...

  9. Epigenetic clock - Wikipedia

    en.wikipedia.org/wiki/Epigenetic_clock

    An epigenetic clock is a biochemical test that can be used to measure age. The test is based on modifications that change over time and regulate how genes are expressed. Typically, the test examines DNA methylation levels, measuring the accumulation of methyl groups to one's DNA molecules, or more recently, based on the histone