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  2. Desiccated thyroid extract - Wikipedia

    en.wikipedia.org/wiki/Desiccated_thyroid_extract

    Desiccated Thyroid became a commercial treatment option in 1934 with Westhroid, [citation needed]. In the early 1960s, desiccated thyroid hormones (thyroid extract) began to be replaced by levothyroxine (synthetic T4), or by combinations of T4 and T3. Replacement occurred faster in the United Kingdom than in North America, but by the 1980s more ...

  3. Levothyroxine - Wikipedia

    en.wikipedia.org/wiki/Levothyroxine

    Levothyroxine is a synthetic form of thyroxine (T 4), which is secreted by the thyroid gland. Levothyroxine and thyroxine are chemically identical: natural thyroxine is also in the "levo" chiral form, the difference is only in terminological preference. T 4 is biosynthesized from tyrosine. Approximately 5% of the US population suffers from over ...

  4. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    Thyroid hormone replacement with levothyroxine treats hypothyroidism. [3] Medical professionals adjust the dose according to symptoms and normalization of the thyroxine and TSH levels. [3] Thyroid medication is safe in pregnancy. [3] Although an adequate amount of dietary iodine is important, too much may worsen specific forms of hypothyroidism ...

  5. Thyroid - Wikipedia

    en.wikipedia.org/wiki/Thyroid

    The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans, it is a butterfly-shaped gland located in the neck below the Adam's apple. It consists of two connected lobes. The lower two thirds of the lobes are connected by a thin band of tissue called the isthmus (pl.: isthmi).

  6. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  7. Thyroxine-binding globulin - Wikipedia

    en.wikipedia.org/wiki/Thyroxine-binding_globulin

    Thyroxine-binding globulin (TBG) is a globulin protein encoded by the SERPINA7 gene in humans. TBG binds thyroid hormones in circulation.It is one of three transport proteins (along with transthyretin and serum albumin) responsible for carrying the thyroid hormones thyroxine (T 4) and triiodothyronine (T 3) in the bloodstream.

  8. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    Euthyroidism: Normal thyroid function; Hypothyroidism: Reduced thyroid function primary hypothyroidism: Feedback loop interrupted by low thyroid secretory capacity, e.g. after thyroid surgery or in case of autoimmune thyroiditis; secondary hypothyroidism: Feedback loop interrupted on the level of pituitary, e.g. in anterior pituitary failure

  9. Hashimoto's thyroiditis - Wikipedia

    en.wikipedia.org/wiki/Hashimoto's_thyroiditis

    Thyroid Peroxidase antibodies are speculated to indicate other autoimmune processes against the placental-fetal unit. [15] Levothyroxine treatment in euthyroid women with thyroid autoimmunity does not significantly impact the relative risk of miscarriage and preterm delivery, or outcomes with live birth.

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