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  2. Degenerative disease - Wikipedia

    en.wikipedia.org/wiki/Degenerative_disease

    Degenerative disease is the result of a continuous process based on degenerative cell changes, affecting tissues or organs, which will increasingly deteriorate over time. [1] In neurodegenerative diseases, cells of the central nervous system stop working or die via neurodegeneration. An example of this is Alzheimer's disease. [2]

  3. Neurodegenerative disease - Wikipedia

    en.wikipedia.org/wiki/Neurodegenerative_disease

    Alzheimer's disease (AD) is a chronic neurodegenerative disease that results in the loss of neurons and synapses in the cerebral cortex and certain subcortical structures, resulting in gross atrophy of the temporal lobe, parietal lobe, and parts of the frontal cortex and cingulate gyrus. [14]

  4. Degeneration (medicine) - Wikipedia

    en.wikipedia.org/wiki/Degeneration_(medicine)

    Degeneration is deterioration in the medical sense. Generally, it is the change from a higher to a lower form. More specifically, it is the change of tissue to a lower or less functionally active form. True degeneration: when there is actual chemical change of the tissue itself.

  5. Neurogenic claudication - Wikipedia

    en.wikipedia.org/wiki/Neurogenic_claudication

    Degenerative changes cause compression of the spinal cord. Degenerative disc disease (DDD) may trigger the pathogenesis of neurogenic claudication. [17] When intervertebral discs degenerate and change shape in DDD, the normal movements of the spine are interrupted.

  6. Degenerative disc disease - Wikipedia

    en.wikipedia.org/wiki/Degenerative_disc_disease

    Degenerative disc disease (DDD) is a medical condition typically brought on by the aging process in which there are anatomic changes and possibly a loss of function of one or more intervertebral discs of the spine. [1] DDD can take place with or without symptoms, but is typically identified once symptoms arise.

  7. Osteoarthritis - Wikipedia

    en.wikipedia.org/wiki/Osteoarthritis

    Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. [5] [6] It is believed to be the fourth leading cause of disability in the world, affecting 1 in 7 adults in the United States alone. [7]

  8. Modic changes - Wikipedia

    en.wikipedia.org/wiki/Modic_changes

    Modic changes are estimated to affect approximately 349 million of the adult population worldwide.[July 2021 est.] [8] Modic changes is a descriptive term used by radiologists in MRI evaluations. Conventional treatment including physiotherapy, chiropractic, acupuncture, and exercise for back pain, are not effective in treating Modic changes.

  9. Wallerian degeneration - Wikipedia

    en.wikipedia.org/wiki/Wallerian_degeneration

    Wallerian degeneration is an active process of degeneration that results when a nerve fiber is ... Another key aspect is the change in permeability of the blood ...