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In the case of women, mean circulating DHT levels have been found to be about 9 ng/dL (0.3 nmol/L) in premenopausal women and 3 ng/dL (0.1 nmol/L) in postmenopausal women. [5] There was no variation in DHT levels across the menstrual cycle in premenopausal women, which is in contrast to testosterone (which shows a peak at mid-cycle). [5]
Dihydrotestosterone, also known as (DHT) will differentiate the remaining male characteristics of the external genitalia. [11] Further sex differentiation of the external genitalia occurs at puberty, when androgen levels again become disparate. Male levels of testosterone directly induce growth of the penis, and indirectly (via DHT) the prostate.
Anecdotal evidence suggests that DHT (dihydrotestosterone), a very potent androgen, can effectively be used for this purpose with minimal side effects. No scientific studies have confirmed this effect in female anatomy, but research targeting the treatment of micropenis has found that local application of DHT is very effective at stimulating ...
5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. They are also sometimes used to treat excess hair growth in women and as a component of hormone therapy for transgender ...
Around 10 to 15% of women with hirsutism have idiopathic hirsutism. [10] Idiopathic hirsutism may be due to increased production of dihydrotestosterone (DHT) in hair follicles and hence may actually still be due to hyperandrogenism. [10] It may be detectable by measurement of DHT or DHT metabolites. [10]
In a placebo-controlled trial, researchers found that two versions of minoxidil (5% and 2%) produced improvements in women affected by female pattern hair loss (FPHL).
5αR2 is expressed in specific tissues and catalyzes the transformation of testosterone (T) to 5α-dihydrotestosterone (DHT). DHT plays a key role in the process of sexual differentiation in the external genitalia and prostate during the development of the male fetus. 5αR2D is a result of impaired 5αR2 activity resulting in decreased DHT levels.
In adulthood, DHT contributes to balding, prostate growth, and sebaceous gland activity. Although androgens are commonly thought of only as male sex hormones, females also have them, but at lower levels: they function in libido and sexual arousal. Androgens are the precursors to estrogens in both men and women.