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Calciseptine has been shown to specifically inhibit the L-type voltage-gated Ca 2+ channels and was the first natural polypeptide discovered with this property. Specific polypeptide inhibitors of voltage-sensitive channels are important tools in research, and were already known for voltage-sensitive Na + channels, both voltage-sensitive and Ca 2+-activated K + channels, and for N-type Ca 2 ...
pentoxyfylline – xanthine derivative used in as an antiinflammatory drug and in the prevention of endotoxemia; pergolide – dopamine receptor agonist used for the treatment of pituitary pars intermedia dysfunction in horses; phenobarbital – anti-convulsant used for seizures; phenylbutazone – nonsteroidal anti-inflammatory drug (NSAID)
The term NSAID is used to refer to a specific drug class that inhibits the conversion of arachidonic acid into prostaglandins and thromboxane. [22] Reduction of prostaglandin helps to reduce pain, decrease vasodilation (and subsequent edema formation), and the diminish the effects of inflammatory mediators such as interleukin-1.
However, any horse that can store excess amounts of glycogen, usually genetic, can develop this form of ER. [1] Recurrent Exertional Rhabdomyolysis (RER) is commonly found in breeds that are high strung such as Arabians and thoroughbreds. However, any horse can develop this type of ER if it displays abnormal muscle contractions. [1]
Detomidine is a sedative with analgesic properties. [3] α 2-adrenergic receptor agonists produce dose-dependent sedative and analgesic effects, mediated by activation of α 2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters.
Acepromazine, acetopromazine, or acetylpromazine (commonly known as ACP, Ace, or by the trade names Atravet or Acezine 2, number depending on mg/ml dose) is a phenothiazine derivative antipsychotic drug. It was used in humans during the 1950s as an antipsychotic, [4] but is now almost exclusively used on animals as a sedative and antiemetic.
Chloral hydrate/magnesium sulfate/pentobarbital sodium, brand name Equithesin, is a combination anesthetic agent used as a general anesthetic in horses. [1] It is administered intravenously to effect. For many years, it was the most commonly used injectable anesthetic in horses.
Printable version; In other projects Wikidata item; Appearance. move to sidebar hide ... Equine estrogens, or horse estrogens, are estrogens found in horses. [1] [2 ...