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  2. Colchicine - Wikipedia

    en.wikipedia.org/wiki/Colchicine

    Trade names for colchicine are Colcrys or Mitigare, which are manufactured as a dark– and light-blue capsule having a dose of 0.6 mg. [26] [76] Colchicine is also prepared as a white, yellow, or purple pill having a dose of 0.6 mg. [76] Colchicine is typically prescribed to mitigate or prevent the onset of gout, or its continuing symptoms and ...

  3. Effective dose (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Effective_dose_(pharmacology)

    The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50 , meaning "effective dose for 50% of the population".

  4. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    The procedure is to take the child's weight in pounds, divide by 150 lb, and multiply the fractional result by the adult dose to find the equivalent child dosage.For example, if an adult dose of medication calls for 30 mg and the child weighs 30 lb, divide the weight by 150 (30/150) to obtain 1/5 and multiply 1/5 times 30 mg to get 6 mg.

  5. Nationwide Children's Hospital - Wikipedia

    en.wikipedia.org/wiki/Nationwide_Children's_Hospital

    In 2003, Children's began an $80 million, 160,000-square-foot (15,000 m 2) clinical expansion and started renovating 100,000 square feet (9,300 m 2) of existing space. Children's became the first freestanding children's hospital in Ohio to receive “Magnet Recognition” in 2004, which is the highest honor for excellence in nursing. [23]

  6. Threshold dose - Wikipedia

    en.wikipedia.org/wiki/Threshold_dose

    Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. [1] At extremely low doses, biological responses are absent for some of the drugs. The increase in dose above threshold dose induces an increase in the percentage of biological responses. [ 2 ]

  7. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    The maximum dose is used, rather than a lower dose, to reduce the number of test subjects (and, among other things, the cost of testing), to detect an effect that might occur only rarely. This type of analysis is also used in establishing chemical residue tolerances in foods. Maximum tolerated dose studies are also done in clinical trials.

  8. Children with Special Healthcare Needs in the United States

    en.wikipedia.org/wiki/Children_with_Special...

    The parents of CSHCN have challenges as well. The study by HRSA, found that the parents of special needs children experience more stress, decreased health, and more questioning of their parenting skills. [3] Despite these challenges, children with SHCN fare better than non-affected children in preventative health care and preventative dental ...

  9. Defined daily dose - Wikipedia

    en.wikipedia.org/wiki/Defined_Daily_Dose

    The WHO's definition is: "The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults." [1] The Defined Daily Dose was first developed in the late 1970s. [2]

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